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Introduction: The state of solitude may be desirable and beneficial particularly for individuals who are highly sensitive and introverted.
Methods: To test these predictions, we surveyed a nationally representative US sample of 301 adults and a sample of 99 undergraduates on their levels of sensory processing sensitivity and assessed introversion with the Big Five Inventory and the multifaceted STAR Introversion Scale. Participants then reported the frequency and duration of their volitional solitude, stress levels, and subjective well-being across 10 consecutive days.
Results: Results revealed that Social Introversion and sensitivity significantly predicted higher motivations for solitude, both self-determined and not. Thinking Introversion also predicted higher self-determined solitude, but BFI introversion showed no relationship with either motivation. Social Introversion and sensitivity predicted higher frequency of solitude in daily life and longer duration of solitary episodes; BFI Introversion and Restrained Introversion showed the opposite pattern for both outcomes. Finally, stress was positively associated with daily solitude frequency, and in turn, solitude frequency was negatively associated with same-day well-being; there were no interaction effects with personality traits.
Discussion: These findings suggest that introversion, as measured by the STAR Introversion Scale, and sensitivity contribute significantly to solitary motivation; however, solitude appears to be sought after by people in times of stress regardless of their scores on these traits.
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http://dx.doi.org/10.1111/jopy.12970 | DOI Listing |
BMC Pediatr
September 2025
Department of Neonatology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China.
Background: Red blood cell (RBC) transfusion is a common intervention for anemia in preterm infants; however, its association with bronchopulmonary dysplasia (BPD) remains debated. While biological mechanisms suggest potential harm, the clinical impact of transfusion frequency on BPD incidence and severity remains unclear.
Objective: To investigate whether RBC transfusion frequency is independently associated with the risk and severity of BPD in preterm infants born before 32 weeks of gestation.
Odontology
September 2025
Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Orthodontic-induced gingival enlargement (OIGE) affects approximately 15-30% of patients undergoing orthodontic treatment and remains largely unpredictable, often relying on subjective clinical assessments made after irreversible tissue changes have occurred. S100A4 is a well-characterized marker of activated fibroblasts involved in pathological tissue remodeling. This was a cross-sectional precision biomarker study that analyzed gingival tissue samples from three groups: healthy controls (n = 60), orthodontic patients without gingival enlargement (n = 31), and patients with clinically diagnosed OIGE (n = 61).
View Article and Find Full Text PDFEur Radiol Exp
September 2025
Center for MR-Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Fetal MRI is increasingly used to investigate fetal lung pathologies, and super-resolution (SR) algorithms could be a powerful clinical tool for this assessment. Our goal was to investigate whether SR reconstructions result in an improved agreement in lung volume measurements determined by different raters, also known as inter-rater reliability.
Materials And Methods: In this single-center retrospective study, fetal lung volumes calculated from both SR reconstructions and the original images were analyzed.
Sci Rep
September 2025
Department of Endocrinology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.
Visceral adiposity has been proposed to be closely linked to cognitive impairment. This cross-sectional study aimed to evaluate the predictive value of Chinese Visceral Adiposity Index (CVAI) for mild cognitive impairment (MCI) in patients with type 2 diabetes mellitus (T2DM) and to develop a quantitative risk assessment model. A total of 337 hospitalized patients with T2DM were included and randomly assigned to a training cohort (70%, n = 236) and a validation cohort (30%, n = 101).
View Article and Find Full Text PDFAcad Radiol
September 2025
Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:
Rationale And Objectives: The diagnostic value of traditional imaging methods and radiomics in predicting macrotrabecular-massive hepatocellular carcinoma (MTM HCC) is yet to be ascertained. Therefore, this meta-analysis aims to compare the diagnostic performance of radiomics and conventional imaging techniques for MTM HCC.
Materials And Methods: Comprehensive publications were searched in PubMed, Embase, Web of Science, and Cochrane Library up to 28 February 2025.