Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Introduction: Sweetpotato faces breeding challenges due to physiological and genomic issues. Gamma radiation is a novel approach for inducing genetic variation in crops. We analyzed the transcriptomic changes in gamma ray-induced sweetpotato mutants with altered stem development compared with those in the wild-type 'Tongchaeru' cultivar.
Methods: RNA sequencing analyses were performed to identify changes in the expression of genes related to stem development.
Results: Transcriptomic analysis identified 8,931 upregulated and 6,901 downregulated genes, including the upregulation of the auxin-responsive () and three () genes. is crucial for regulating the expression of early auxin-responsive genes and stem growth in . In the mutant, several genes related to stem elongation, including and those involved in various signaling pathways such as auxin and gibberellin, were upregulated.
Discussion: Our results suggest that gamma ray-induced mutations influence auxin-dependent stem development by modulating a complex regulatory network involving the expression of and genes, and other signaling pathways such as gibberellin and ethylene signaling genes. This study enhances our understanding of the regulatory mechanisms underlying stem growth in sweetpotato, providing valuable insights for genomics-assisted breeding efforts.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322061 | PMC |
| http://dx.doi.org/10.3389/fgene.2024.1419399 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Transformative Therapies for Wound Care: Insights into Tissue Engineering and Regenerative Medicine.
Adv Exp Med Biol
September 2025
Department of Stem Cells & Regenerative Medicine, Center for Interdisciplinary Research, D. Y. Patil Education Society (Deemed to be University), Kolhapur, Maharashtra, India.
Wound healing is a dynamic and complex process that consists of four interconnected phases: hemostasis, inflammation, proliferation, and remodeling. This complex process is based on the coordinated actions of growth factors, cytokines, and other cellular interactions. However, conditions such as diabetes and chronic illnesses can disrupt this process and lead to nonhealing wounds or chronic ulcers.
View Article and Find Full Text PDFEngineering a cell-free bone regeneration platform using osteogenically primed MSC-EVs and nHAp-enriched IPN hydrogels.
Regen Med
September 2025
Symbiosis Centre for Stem Cell Research (SCSCR), Symbiosis School of Biological Sciences (SSBS), Symbiosis International, Deemed University, Lavale, Pune, India.
Aims: This study aimed to enhance the osteoinductive potential of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) by integrating them into a nano-hydroxyapatite (nHAp)-enriched hydrogel scaffold for bone regeneration applications.
Materials & Methods: EVs were isolated from naïve and osteogenically primed MSCs and characterized for morphology, cargo content, and cytocompatibility. Their uptake and osteoinductive activity were assessed using MC3T3 cells within a 3D interpenetrating network (IPN) hydrogel.
Elevated ozone promotes the dominance of invasive plant species in low-diversity native plant communities.
Am J Bot
September 2025
Shandong Key Laboratory of Eco-Environmental Science for Yellow River Delta, Shandong University of Aeronautics, Binzhou, Shandong, China.
Premise: The diversity-invasibility hypothesis suggests that native plant communities with high species diversity are more resistant to invasions by exotic species compared to those with fewer species. This resistance stems from more complete resource use and stronger biotic interactions in diverse communities, which limit opportunities for invaders to establish. However, this resistance could potentially be weakened by environmental stressors, including elevated tropospheric ozone.
View Article and Find Full Text PDFEffects of Donor Cell Type on Developmental Competence of Canine-Porcine Interspecies Cloned Embryos.
Reprod Domest Anim
September 2025
National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, China.
Canine somatic cell nuclear transfer (SCNT) is a powerful technology that can be used to clone beloved companion dogs, produce valuable working dogs, rescue endangered canine breeds, and create genetically engineered dogs. Nevertheless, the application of this technology is hindered by the low developmental efficiency of canine SCNT embryos. It has been shown that in pig and horse cloning using mesenchymal stem cells (MSCs), compared with fibroblasts, as donor cells can enhance the developmental potential of SCNT embryos.
View Article and Find Full Text PDFAdvancing Targeted Drug Delivery in Glioblastoma Multiforme Through Biomimetic Nanomedicine Using 3D Tumor-On-a-Chip Model.
Adv Healthc Mater
September 2025
School of Biological and Health Systems Engineering (SBHSE), Arizona State University, Tempe, AZ, 85287, USA.
The prognosis of glioblastoma multiforme (GBM) remains dismal, despite standard treatment regimens. A key challenge in treating GBM is the persistence of glioma stem cells (GSCs) within the perivascular niche (PVN) - a protective tumor microenvironment (TME) that is often associated with inadequate drug penetration. Current preclinical models do not capture complexity of the human TME, particularly the vasculature and niche-specific interactions that drive GBM progression.
View Article and Find Full Text PDF