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Introduction: Intracranial hemorrhages present across a spectrum of clinical phenotypes, with many patients transferred across hospitals to access higher levels of neurocritical care. We sought to characterize patient dispositions following intracranial hemorrhage and examine disparities associated with interhospital transfers.
Methods: Using the Healthcare Cost and Utilization Project database, we mapped and identified factors influencing the likelihood of patient transfers and receipt of specialist interventional procedures following intracranial hemorrhage.
Results: Of 11,660 patients with intracranial hemorrhage, 59.4% had non-traumatic and 87.5% single compartment bleeds. After presentation, about a quarter of patients were transferred to another facility either directly from the ED (23.0%) or after inpatient admission (1.8%). On unadjusted analysis, patients who were white, in the upper income quartiles, with private insurance, or resided in suburban areas were more frequently transferred. After adjusting for patient-and hospital-level variables, younger and non-white patients had higher odds of transfer. Hospital capabilities, residence location, insurance status, and prior therapeutic relationship remained as transfer predictors. Transferred patients had a similar hospital length of stay compared to admitted patients, with 43.1% having no recorded surgical or specialist interventional procedure after transfer.
Discussion: Our analysis reveals opportunities for improvement in risk stratification guiding transfers, as well as structural challenges likely impacting transfer decisions.
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http://dx.doi.org/10.3389/fneur.2024.1409713 | DOI Listing |
Forensic Sci Int
August 2025
Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada.
We report the forensic and clinicopathological spectrum of 14 postmortem cases involving the vertebral artery. In all cases, there was either pontocerebellar infarction (n = 8) or subarachnoid hemorrhage (n = 6). The underlying pathology of the vertebral artery was segmental mediolytic arteriopathy (n = 5), traumatic rupture of the arterial wall (n = 3), arterial dissection (n = 2), or atherosclerosis (n = 4).
View Article and Find Full Text PDFComput Biol Med
September 2025
Department of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Intracranial aneurysms (IAs) are common vascular pathologies with a risk of fatal rupture. Human assessment of rupture risk is error prone, and treatment decision for unruptured IAs often rely on expert opinion and institutional policy. Therefore, we aimed to develop a computer-assisted aneurysm rupture prediction framework to help guide the decision-making process and create future decision criteria.
View Article and Find Full Text PDFNeurochem Res
September 2025
Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Intracerebral hemorrhage (ICH) is a common yet severe cerebrovascular disorder associated with high morbidity, disability, and mortality rates. Kaempferol (Kae), a natural flavonoid with potent antioxidant and anti-inflammatory properties, has shown promise in neuroprotection; however, its therapeutic potential in promoting neurological recovery after ICH remains unclear. In this study, we investigated the neuroprotective effects of Kae in ICH and explored its underlying mechanisms using in vitro and in vivo models.
View Article and Find Full Text PDFMed Sci Monit
September 2025
Department of Neurology, Chongqing University Three Gorges Hospital, Chongqing, China.
BACKGROUND Multiple factors impact the prognosis of intracerebral hemorrhage (ICH). This study aimed to evaluate prognosis at 90 days after ICH in 561 patients using the numerical rating scale (NRS), the Braden scale, the Morse fall risk scale (MFS), and the enhanced modified early warning (MEW) scale. MATERIAL AND METHODS A retrospective study was performed among 561 patients with ICH diagnosed in our hospital.
View Article and Find Full Text PDFSci Rep
September 2025
Department of Neurosurgery, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, Moorenstraße 5, 40225, Duesseldorf, Germany.
Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition associated with high rates of morbidity and mortality, mainly due to post-hemorrhagic complications such as cerebral vasospasm (CVS) and delayed cerebral ischemia (DCI). Recent evidence implicates platelet activation and inflammatory mediators in the cascade of secondary injury following aSAH. Monitoring and timely treatment of post-SAH complications is critical to improve clinical outcomes.
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