Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamadermatol.2024.2311DOI Listing

Publication Analysis

Top Keywords

rapid improvement
4
improvement refractory
4
refractory acute
4
acute generalized
4
generalized exanthematous
4
exanthematous pustulosis
4
pustulosis spesolimab
4
rapid
1
refractory
1
acute
1

Similar Publications

Background: The rapid advancement of next-generation sequencing has significantly expanded the landscape of precision medicine. However, health care professionals face increasing challenges in keeping pace with the growing body of oncological knowledge and integrating it effectively into clinical workflows. Precision oncology decision support (PODS) tools aim to assist clinicians in navigating this complexity, yet their current functionalities only partially address clinical needs.

View Article and Find Full Text PDF

Rationale: Modulator therapies like ivacaftor have revolutionized clinical management of cystic fibrosis (CF), showing marked short-term benefits in trials but heterogeneous findings in long-term observational studies. Since newer modulators have become the standard of care for the majority living with CF in the U.S.

View Article and Find Full Text PDF

With the rapid development of industrial automation and intelligent manufacturing, defect detection of electronic products has become crucial in the production process. Traditional defect detection methods often face the problems of insufficient accuracy and inefficiency when dealing with complex backgrounds, tiny defects, and multiple defect types. To overcome these problems, this paper proposes Y-MaskNet, a multi-task joint learning framework based on YOLOv5 and Mask R-CNN, which aims to improve the accuracy and efficiency of defect detection and segmentation in electronic products.

View Article and Find Full Text PDF

Characterization and Antimicrobial Efficacy of a Bacteriophage Targeting Multidrug-Resistant .

ACS Infect Dis

September 2025

Animal-Derived Food Safety Innovation Team, College of Veterinary Medicine, Anhui Agricultural University, Hefei 230036, China.

The emergence of multidrug-resistant (MDR) poses a significant threat to global public health, necessitating alternative therapeutic strategies. In this study, we isolated and characterized a novel lytic bacteriophage (phage), vB_EcoM_51, from poultry farm sewage and evaluated its potential against MDR . Transmission electron microscopy revealed that the phage exhibits morphological features typical of the family, including a polyhedral head (∼66.

View Article and Find Full Text PDF

Since the 2013-2014 Ebola virus disease outbreak, Guinea has faced recurrent epidemics of viral hemorrhagic fevers. Although the country has learned from these epidemics by improving its disease surveillance and investigation capacities, local authorities and stakeholders, including community actors, are not sufficiently involved in the disease-emergence response. As a result, measures are not fully understood and have failed to engage local stakeholders.

View Article and Find Full Text PDF