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This systematic review and meta-analysis aimed to investigate the prevalence of self-reported sleep disturbances in people living with HIV considering the effects of age, depression, anxiety, CD4 cell counts, time since HIV diagnosis, study region, and the instruments used to measure sleep disturbances. We searched PubMed, PsycINFO, and EMBASE to include eligible articles. In this meta-analysis of 43 studies, the pooled prevalence of self-reported sleep disturbances was 52.29% (95% confidence interval 47.69-56.87). The subgroup analyses revealed that variations in the sleep measurements and study region significantly contributed to the observed heterogeneity. In the meta-regression analyses, higher proportions of participants with depression or anxiety and longer times since HIV diagnosis were significantly associated with a higher prevalence of self-reported sleep disturbances after adjusting for mean age. Our findings emphasise the substantial burden of sleep disturbances in people living with HIV and identified comorbid depression and anxiety and the time since HIV diagnosis as significant moderators. These results underscore the importance of considering these factors when designing tailored screening programmes for high-risk patients and implementing early interventions to prevent and mitigate sleep disturbances in people living with HIV.
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http://dx.doi.org/10.1038/s41598-024-65713-x | DOI Listing |
JAMA Netw Open
September 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: As obesity rates rise in the US, managing associated metabolic comorbidities presents a growing burden to the health care system. While bariatric surgery has shown promise in mitigating established metabolic conditions, no large studies have quantified the risk of developing major obesity-related comorbidities after bariatric surgery.
Objective: To identify common metabolic phenotypes for patients eligible for bariatric surgery and to estimate crude and adjusted incidence rates of additional metabolic comorbidities associated with bariatric surgery compared with weight management program (WMP) alone.
Int J Soc Psychiatry
September 2025
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Background: Climate distress is a psychological reaction to adverse weather events and climate change. These events can increase people's vulnerability to develop psychiatric disorders like anxiety, depression, and PTSD particularly in disaster-prone regions like India.
Aim: To explore the relationship between climate distress and psychological impact with a particular emphasis on women, elderly, and other at risk populations who owing to their health vulnerabilities, lack of resources or social roles that make them dependent on others, experience stress in the face of climate change.
Nat Sci Sleep
September 2025
Department of Exercise Physiology, School of Sport Science, Beijing Sport University, Beijing, People's Republic of China.
Purpose: Depression patients frequently report sleep disorder. Aerobic exercise is believed to improve sleep quality, but its effect on the overall sleep of depressed patients remains uncertain. This study systematically evaluates the effects of aerobic exercises at different intensities on subjective and objective sleep quality in participants diagnosed with depression or at high risk of depression, from studies covering various depression subtypes (including but not limited to geriatric depression, prenatal depression, and poststroke depression), and examines changes in depression, anxiety, and quality of life following aerobic exercise.
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August 2025
Division of Public Health, Department of Family and Preventive Medicine, University of Utah, 303 Chipeta Way, Salt Lake City, UT 84013, United States of America.
Individuals with mild cognitive impairment (MCI) demonstrate cognitive decline without major functional impairment and are at increased risk for developing Alzheimer's disease and related dementias (ADRD). Sleep and biobehavioral rhythm disturbances (disruptions in 24-h oscillations in physiology and behavior, including rest-activity patterns and mealtimes) are more than twice as common among patients with MCI than cognitively intact older adults. Importantly, the consequences of sleep and biobehavioral rhythm disruption in MCI extend beyond the patient, also profoundly affecting the spouse/partner.
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