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http://dx.doi.org/10.1038/s41586-024-07416-x | DOI Listing |
J Med Virol
September 2025
S. A. Büyüktuna, S.
View Article and Find Full Text PDFTurk J Pharm Sci
September 2025
İstanbul University Faculty of Pharmacy, Department of Pharmaceutical Chemistry, İstanbul, Türkiye.
Objectives: This study focused on synthesizing and characterizing novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety and evaluating their antimicrobial activity against several bacterial strains. The research aimed to identify key structural features that enhance antimicrobial efficacy through structure-activity relationship analysis and identify the minimum inhibitory concentration (MIC) of the most potent compounds to assess their potential for further development as antimicrobial agents.
Materials And Methods: Nine novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety were synthesized by reacting 1,2,4-triazole derivatives with thiosemicarbazide precursors, and the products were characterized using infrared spectroscopy, proton nuclear magnetic resonance (H-NMR), carbon-13 nuclear magnetic resonance (C-NMR) spectroscopy, and elemental analysis.
Water Res
August 2025
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, China. Electronic address:
Global phosphorus (P) resources are facing a depletion crisis, and pyrolysis of P-rich sewage sludge (SS) offers significant resource potential. Optimizing pyrolysis conditions remains key yet challenging for enhancing P retention and bioavailability. This study conducted a correlation-prediction-causation integrated framework (CPCIF) to investigate how heating temperature (HT), heating rate (HR), and retention time (RT) influence total P enrichment rate (BTPE), relative inorganic P transformation rate (BITP), and relative apatite P transformation rate (BAIP) from SS to biochar during pyrolysis.
View Article and Find Full Text PDFAnn Surg Oncol
September 2025
Department of Surgery, Tokushima University, Tokushima, Japan.
Background: Although magnification is an advantage of robotic liver resection (RLR) as it enables precise surgery, the direction of parenchymal dissection, the vascular anatomy, and the tumor location can sometimes be lost. Extended reality (XR) has advantages over other navigation systems in terms of spatial awareness, sharing, and simplicity, and it also has the potential to overcome some of the limitations of RLR. METHODS: In this video, we demonstrate innovative RLR with XR by three separate surgeons.
View Article and Find Full Text PDFPurpose: This study aims to validate the usefulness of T10-pelvic angle (T10PA) in predicting pelvic tilt (PT) restoration, proximal junctional kyphosis (PJK) development, and clinical outcomes after adult spinal deformity (ASD) surgery.
Methods: This retrospective study included 213 ASD patients who underwent fusion from the lower thoracic spine (T9 or T10) to the pelvis. T10PA was measured on 6-week postoperative radiographs as the angle between the center of T10 and the hip center, and from the hip center to the midpoint of the S1 upper endplate.