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Objectives: The aim of this review is to focus on the possibility of patients with squamous cell carcinoma to develop a second primary disease such as DLBCL, perhaps because of the irradiation of the head and neck area.
Materials And Methods: A case of an 89-year-old man is reported, who initially underwent surgical and complementary treatment for neck squamous cell carcinoma of occult primary and later for tonsillar diffuse large B-cell non-Hodgkin lymphoma.
Results: The second primary was considered a recurrence in the neck of the original cancer of unknown primary, so a new surgical management was decided. The final pathology report described a diffuse large B-cell non-Hodgkin lymphoma.
Conclusions: The importance of maintaining follow-ups for patients with occult primary cancers who are at an elevated risk of developing a metastasis or a second primary carcinoma outbreak is highlighted.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11130887 | PMC |
http://dx.doi.org/10.3390/hematolrep16020026 | DOI Listing |
J Am Coll Health
September 2025
Hubbard School of Journalism and Mass Communication, University of Minnesota, Minneapolis, Minnesota, USA.
: An evolving THC product marketplace is diffusing through college campuses. It is essential to understand college students' THC knowledge, attitudes, practices and product packaging perceptions to identify campus health education and messaging strategies. : Participants were 30 undergraduate college students at a large-midwestern, public university.
View Article and Find Full Text PDFPhys Rev Lett
August 2025
Università degli Studi di Padova, Dipartimento di Fisica e Astronomia, Via Marzolo 8, 35131 Padova, Italy.
Feebly interacting particles, such as sterile neutrinos, dark photons, and axions, can be abundantly produced in the proto-neutron star (PNS) formed in core-collapse supernovae (CCSNe). These particles can decay into photons or charged leptons, depositing energy outside the PNS. Strong bounds on new particles can thus be derived from the observed luminosity of CCSNe, with even tighter bounds obtained from low-energy SNe observations.
View Article and Find Full Text PDFPhys Rev Lett
August 2025
Central China Normal University, Key Laboratory of Quark and Lepton Physics (MOE) and Institute of Particle Physics, Wuhan 430079, China.
Diffusion wake accompanying a Mach cone is a unique feature of the medium response to projectiles traveling at a speed faster than the velocity of sound. This is also the case for jet-medium interaction inside the quark-gluon plasma in high-energy heavy-ion collisions. It leads to a depletion of soft hadrons in the opposite direction of the propagating jet and, recently, has been observed in Z-jet events of Pb+Pb collisions at LHC.
View Article and Find Full Text PDFAnn Hematol
September 2025
Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Approximately 30-40% of diffuse large B-cell lymphoma (DLBCL) patients will develop relapse/refractory disease, who may benefit from novel therapies, such as CAR-T cell therapy. Thus, accurate identification of individuals at high risk of early chemoimmunotherapy failure (ECF) is crucial. Methods.
View Article and Find Full Text PDFSmall
September 2025
School of Chemistry and Chemical Engineering, Guangxi Key Laboratory of AI-Driven Zero-Carbon Technologies, Key Laboratory of New Low-carbon Green Chemical Technology Education Department of Guangxi Zhuang Autonomous Region, Guangxi University, Nanning, 530004, China.
Sarcosine (Sar), a critical potential biomarker for prostate cancer (PCa), is primarily detected via enzyme cascade reactions involving sarcosine oxidase (SOx) and peroxidase. Nevertheless, the intermediate product hydrogen peroxide (HO) tends to diffuse to the bulk solution phase without entering subsequent reaction, leading to suboptimal detection sensitivity and compromised analytical performance. To tackle this challenge, a multilayered sandwich nanozyme cascade sensor (designated as Cu-MOF/Rf@BDC) is proposed through a confinement-mediated HO enrichment strategy.
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