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Study Design: Prospective case series.
Prcis: This prospective study determines which formulas can best predict the refractive outcome in patients with primary angle closure disease (PACD) after cataract surgery.
Objective: To compare the accuracy of 6 intraocular lens power calculation formulas, Barrett Universal II (BU II), Haigis, Hoffer Q, Holladay I, Kane and SRK/T, in eyes with PACD.
Patients And Methods: Patients diagnosed with PACD and cataracts and who met the indication for cataract surgery were enrolled in the study. Six intraocular lens power calculation formulas were used to calculate the refractive diopter. The percentage of eyes with prediction error (PE) within ±0.50 D and the median absolute PE were compared to determine the accuracy of different formulas in patients with PACD. Subgroup analysis was performed according to axial length (AL). The accuracy of BU II was compared between patients with PACD and patients with age-related cataracts.
Results: One hundred five patients (105 eyes) with PACD and 35 patients (35 eyes) with age-related cataracts were enrolled in the study. Haigis, Kane, and BU II formula achieved a comparable outcome and outperformed over the other 3 formulas in patients with PACD. Subgroup analysis showed that the group with long AL has lower values of median absolute PE. PE was significantly positively correlated with AL and negatively correlated with relative lens position when calculated using BU II and Kane.
Conclusions: Haigis, Kane, and BU II formula achieved a comparable outcome and outperformed over the other 3 formulas in patients with PACD.
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http://dx.doi.org/10.1097/IJG.0000000000002430 | DOI Listing |
Dermatitis
September 2025
From the Division of Dermatology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.
There are limited data regarding photopatch testing (PPT) in Israel. To investigate the prevalence of positive reactions and concurrent diagnosis of patients that underwent PPT in a single center in Israel. Retrospective cohort study that included all patients that were suspected of having contact dermatitis and underwent patch testing with the European baseline series (EBS) and additionally were selectively PPT with the Scandinavian/European baseline photopatch series in a tertiary medical center in Israel (2009-2023).
View Article and Find Full Text PDFOphthalmol Glaucoma
August 2025
Institute of Ophthalmology, University College London, London, United Kingdom.
Primary angle-closure disease (PACD) remains a significant cause of visual morbidity globally, particularly in Asia, where >18.5 million will have primary angle-closure glaucoma (PACG) by 2050. Although glaucomatous optic neuropathy is the most widely recognized cause of visual loss, PACD significantly impacts a range of anterior and posterior segment structures and physiological processes, such as corneal endothelial cell loss, trabecular meshwork structural changes and functional derangement, lens opacities, iris ischemia causing a dilated pupil and consequent degradation in vision, retinal vein occlusions, rapidly evolving pressure-related retinal ischemia, and increased surgical morbidity including aqueous misdirection and zonulopathy.
View Article and Find Full Text PDFJ Clin Med
July 2025
Department of Ophthalmology, Kyorin University School of Medicine, Mitaka 181-8611, Japan.
Patients with primary angle-closure disease (PACD), those with no history of acute angle-closure glaucoma or laser iridotomy, rarely present with prominent corneal endothelial cell density (CECD) loss. To identify factors associated with decreased CECD in PACD, anterior segment parameters were compared in patients with PACD and normal CECD and patients with PACD and decreased CECD, using anterior segment optical coherence tomography (AS-OCT). Ten patients with PACD and CECD of less than 1500/mm without a history of cataract surgery, acute angle-closure glaucoma, or prior laser glaucoma procedures were identified at the Kyorin Eye Center from January 2018 to July 2023.
View Article and Find Full Text PDFOphthalmol Ther
August 2025
Department of Ophthalmology, Peking University People's Hospital, No.11 Xizhimen South Street, Xicheng District, Beijing, 100044, China.
Introduction: The mechanism of primary angle closure disease (PACD) has been extensively investigated, while some cases remain unexplained. Hypothesizing that chronic primary ciliary block (CB) may play a role in PACD pathogenesis and the contribution could be revealed by pharmacologic cycloplegia and mydriasis, this study analyzed changes in anterior segment biometric parameters following cycloplegic intervention.
Methods: A total of 170 eyes of 170 Chinese subjects aged between 50 and 80 years were included: 90 in the primary angle closure suspect (PACS) group, 33 in the primary angle closure (PAC)/PAC glaucoma (PACG) group, and 47 in the normal control group.
J Glaucoma
September 2025
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.
Prcis: The presence of anterior capsular laxity caused acute angle closure glaucoma, and posterior capsular laxity alone was associated with a chronic progressive course, revealing new insight into the pathogenesis of primary angle closure disease.
Purpose: This study investigates the association between anterior or posterior capsular bag laxity during cataract surgery and clinical characteristics in patients with primary angle closure disease (PACD).
Methods: This retrospective study included 137 patients (200 eyes) diagnosed with PACD and undergoing phacoemulsification cataract surgery.