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Purpose: Construct an exercise intervention program for patients with sarcopenic obesity.
Material And Methods: Based on the COM-B theoretical model and evidence-based principles, the program was constructed using qualitative methods of literature analysis and Delphi method. The Delphi panel consisted of 15 experts from the fields of clinical medicine, rehabilitation medicine, medical technology, and nursing.
Results: Fifteen experts were consulted, and the consultation recovery rate was 100%; the authority coefficient of the 1st round was 0.83, with coefficients of variation ranging from 0.00 to 0.27, and importance scores ranging from (4.13±1.13) to (5±0); the authority coefficient of the 2nd round was 0.82, with coefficients of variation ranging from 0.00 to 0.20, and importance scores ranging from (4.53±0.64) to (5±0); Kendall's harmony coefficient was 0.102, 0.115, respectively, and the differences were statistically significant(P < 0.05). The constructed exercise intervention program for patients with sarcopenic obesity included 4 primary indicators, 12 secondary indicators, and 28 tertiary indicators.
Conclusion: The constructed exercise intervention program for patients with sarcopenic obesity is scientific, feasible and generalizable, and can provide useful reference for related personnel to develop exercise programs for patients with sarcopenic obesity.
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http://dx.doi.org/10.2147/CIA.S455849 | DOI Listing |
Cureus
August 2025
Internal Medicine, Malcom Randall Veterans Affairs Medical Center, Gainesville, USA.
Dysphagia lusoria is an uncommon cause of dysphagia with an increasing incidence with age. It is unknown why individuals with dysphagia lusoria typically remain asymptomatic until older adulthood, but some theorize that it could be related to physiologic and anatomical changes that occur with the aging process, such as increased esophageal rigidity and stiffening of vascular walls with atherosclerosis, that make the compression from these congenital aberrations more impactful. While uncommon, it is also likely underrecognized due to its being diagnostically challenging to identify.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
August 2025
Division of Biochemistry and Molecular Biology, Siberian State Medical University, Ministry of Health of the Russian Federation, 634050 Tomsk, Russia.
Background: Sarcopenia is a complex, multifactorial condition characterized by progressive loss of muscle mass, strength, and function. Despite growing awareness, the early diagnosis and pathophysiological characterization of this condition remain challenging due to the lack of integrative biomarkers.
Objective: This study aimed to conduct a comprehensive multilevel profiling of clinical parameters, immune cell phenotypes, extracellular vesicle (EV) signatures, and biochemical markers to elucidate biological gradients associated with different stages of sarcopenia.
Surg Oncol
September 2025
Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Liebigstr. 20, 04103, Leipzig, Germany. Electronic address:
Introduction: Body composition including low skeletal muscle mass (LSMM) defined by skeletal muscle index (SMI) and subcutaneous and visceral adipose tissue (SAT and VAT) can be assessed using cross-sectional imaging techniques. Previous studies have shown promising prognostic value for several tumour entities, including esophageal cancer (EC). The aim of this study was to analyse possible associations of body composition parameters in patients with esophageal cancer undergoing curative treatment.
View Article and Find Full Text PDFInt J Gen Med
August 2025
Nutrition Department, Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.
Purpose: This study aimed to evaluate the individual and joint associations of malnutrition and obesity on predicting the severity and prognosis of acute pancreatitis (AP).
Patients And Methods: A retrospective analysis of 240 AP patients was conducted. Malnutrition was diagnosed using Global Leadership Initiative on Malnutrition (GLIM) criteria.
Eur J Radiol
August 2025
Department of Health Management, Tianjin Hospital, No. 406 Jiefang South Road, Hexi District, Tianjin 300211, China.
Purpose: Although the clinical implication of sarcopenia has been verified in the context of cirrhosis, there is limited data concerning cut-offs of CT-measured skeletal muscle index (SMI) across different ethnicities. We aimed to compare the predictive performance of distinct SMI values-defined sarcopenia for prognosis in cirrhosis.
Methods: Totally, 478 inpatients due to cirrhosis-associated acute insults were prospectively enrolled.