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With the continuous rise of the sea cucumber aquaculture industry in China, the tropical sea cucumber aquaculture industry is also improving. However, research on the gut microorganisms of tropical sea cucumbers in captivity is scarce. In this study, high-throughput sequencing methods were used to analyze the gut microbial composition of and in the dry season and wet season of artificial environments. The results showed that 66 phyla were obtained in all samples, of which 59 phyla were obtained in the dry season, and 45 phyla were obtained in the wet season. The Tax4Fun analysis showed that certain gut bacterial communities affect the daily metabolism of two sea cucumber species and are involved in maintaining gut microecological balance in the gut of two sea cucumber species. In addition, compared with differences between species, PCoA and UPGMA clustering analysis showed the gut prokaryotes of the same sea cucumber species varied more in different seasons, indicating that the influence of environment was higher than the feeding choices of sea cucumbers under relatively closed conditions. These results revealed the gut bacterial community composition of and and the differences in gut bacterial structure between two sea cucumber species in different seasons were compared, which would provide the foundation for tropical sea cucumber aquaculture in the future.
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http://dx.doi.org/10.3390/ijms25084573 | DOI Listing |
Zool Res
September 2025
State Key Laboratory of Agricultural Products Safety, Ningbo University, Ningbo, Zhejiang 315211, China.
Apoptosis preserves organismal homeostasis by selectively eliminating unnecessary or damaged cells, with accumulating evidence also suggesting that it activates regenerative pathways and facilitates tissue remodeling. To date, however, the regulatory mechanisms linking this form of programmed cell death to regeneration remain poorly defined, particularly in evolutionarily basal organisms. Using the sea cucumber ( ) as a model for intestinal regeneration, this study identified robust apoptotic activity across key regenerative stages.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Departments of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.. Electronic address:
A naturally derived library of glycomimetic mimicking the structure-function of heparan sulfate (HS) remains an untapped reservoir for drug discovery against viral infections. In this work we screened a library of marine-derived sulfated glycans from seaweeds and sea cucumbers to investigate if they can compete for the ligand/receptor binding sites to prevent virus entry. Multiple promising candidates were identified, such as RPI-27 (IC: 1.
View Article and Find Full Text PDFGenome
September 2025
Møreforsking AS Ålesund, Alesund, Møre og Romsdal, Norway;
The sea cucumber is an important holothuroid species inhabiting the eastern North Atlantic Ocean benthic zone at depths from about 20 - 3000 m. Geographical distribution is from the Barents Sea in the north to the Canary Islands in the south. Along with the increasing commercial interest of new sea cucumber species, research into sea cucumber biology has also advanced.
View Article and Find Full Text PDFZoolog Sci
August 2025
Meguro Parasitological Museum, Meguro, Tokyo 153-0064, Japan.
Snails of the family Eulimidae are parasites of echinoderms in all five extant classes. Despite long years of taxonomic research on Eulimidae in Japan, their local species richness remains to be investigated, and few studies have focused on a eulimid fauna of a certain echinoderm taxon, even if it is a common species. Here, we conducted a comprehensive sampling of species parasitizing the black sea cucumber in Shirahama, Wakayama, central Japan.
View Article and Find Full Text PDFBiology (Basel)
August 2025
Key Laboratory of Mariculture and Stock Enhancement in North China's Sea (Ministry of Agriculture and Rural Affairs), Dalian Ocean University, Dalian 116023, China.
The histological integrity of the intestine depends on the tight and orderly arrangement of epithelial cells within the intestinal villi. , a transforming growth factor-β (TGF-β) family member, has been reported to promote epithelial cell proliferation. Collagen not only establishes physical connections between adjacent cells but also serves as an anchoring platform for cell adhesion and regeneration processes.
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