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Purpose Of Review: Speckle-tracking echocardiography (STE) can assess myocardial motion in non-LV chambers-including assessment of left atrial (LA) and right ventricular (RV) strain. This review seeks to highlight the diagnostic, prognostic, and clinical significance of these parameters in heart failure, atrial fibrillation (AF), diastolic dysfunction, pulmonary hypertension (PH), tricuspid regurgitation, and heart transplant recipients.
Recent Findings: Impaired LA strain reflects worse LV diastolic function in individuals with and without HF, and this is associated with decreased exercise capacity. Initiating treatments targeting these functional aspects may enhance exercise capacity and potentially prevent heart failure (HF). Impaired LA strain also identifies patients with a high risk of AF, and this recognition may lead to preventive strategies. Impaired RV strain has significant clinical and prognostic implications across various clinical scenarios, including HF, PH, tricuspid regurgitation, or in heart transplant recipients. STE should not be limited to the assessment of deformation of the LV myocardium. The use of LA and RV strain is supported by a substantial evidence base, and these parameters should be used more widely.
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http://dx.doi.org/10.1007/s11886-024-02058-x | DOI Listing |
JCI Insight
September 2025
Department of Physiology and Neurobiology, University of Connecticut, Storrs, United States of America.
Dravet syndrome (DS) is an early-onset epilepsy caused by loss of function mutations in the SCN1A gene, which encodes Nav1.1 channels that preferentially regulate activity of inhibitory neurons early in development. DS is associated with a high incidence of sudden unexpected death in epilepsy (SUDEP) by a mechanism that may involve respiratory failure.
View Article and Find Full Text PDFArch Gynecol Obstet
September 2025
The First Affiliated Hospital of Soochow University, No. 899 Pinghai Street, Suzhou, Jiangsu, China.
Objective: The study utilized non-invasive myocardial work indices to investigate myocardial injury in infants born to mothers with severe preeclampsia (SPE) and to explore the duration of this myocardial damage during the neonatal period.
Methods: This prospective study included 34 preterm infants born to mothers with SPE and 28 preterm infants born to mothers without severe pregnancy complications (termed "controls"). Echocardiography was performed in infants within 24 h of birth, then again at 48-72 h and 14-28 days, to obtain echocardiographic parameters.
Biotechnol Bioeng
September 2025
Department of Biosystems Engineering, Auburn University, Auburn, Alabama, USA.
Ensuring sufficient crop yields in an era of rapid population growth and limited arable land requires innovative strategies to enhance plant resilience and sustain, or even improve, growth and productivity despite environmental stress. Besides symbiotic nitrogen fixation, rhizobia may play a central role in sustainable agriculture by alleviating the detrimental effects of ethylene-a key stress hormone in plants-especially under conditions like drought through the deamination of 1-aminocyclopropane-1-carboxylic acid (ACC). In this study, we focused on genetically engineering a new Bradyrhizobium sp.
View Article and Find Full Text PDFAppl Psychol Health Well Being
October 2025
Department of Educational Sciences, Masaryk University, Faculty of Arts, Czech Republic.
Burnout and perceived work ability (PWA) are critical factors influencing teachers' professional well-being and effectiveness. The potential bidirectional relationship between these constructs remains underexplored, particularly in primary and lower secondary school teachers. This study examines the reciprocal relationship between burnout and PWA among teachers over time, using the job demands-resources (JD-R) model and the conservation of resources (COR) theory.
View Article and Find Full Text PDFEchocardiography
September 2025
Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Objectives: To explore the relationships between cardiac parameters and body composition indices, identifying predictors of subclinical cardiac systolic dysfunction.
Methods: Using anthropometric and serological parameters, echocardiography, and body composition analysis, this study evaluated metabolic profiles, cardiac remodeling patterns, and body composition characteristics in young adult obese patients, while quantifying the correlations between cardiac parameters and body composition indices. Subclinical left ventricular systolic dysfunction was defined as global longitudinal strain (GLS) < 18%.