The broader health benefits of optimised dietary thresholds proposed for type 2 diabetes prevention in Aotearoa New Zealand: simulation modelling.

N Z Med J

Professor of Nutrition and Medicine, Department of Medicine, University of Otago, Dunedin; Edgar Diabetes and Obesity Research Centre, Department of Medicine, University of Otago, Dunedin; Riddet Institute Centre of Research Excellence, Palmerston North; The Healthier Lives National Science Challeng

Published: March 2024


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Aim: Optimised dietary thresholds for type 2 diabetes prevention exist; however, they likely have additional benefits beyond diabetes prevention. We have modelled the effects of the proposed dietary thresholds on Health-Adjusted Life Years (HALY), health inequities and health system cost in Aotearoa New Zealand.

Methods: We created a national diet scenario using the optimised thresholds and compared it with current intakes using an established multistate life table. The primary model considered change in outcome from increasing intakes of fruits, vegetables, nuts and seeds while decreasing red meat and sugar-sweetened beverages. A separate secondary nutrient-based model considered change due to increasing whole grains and yoghurt while decreasing refined grains, potatoes and fruit juice. Both models considered the direct non-weight mediated associations between diet and disease.

Results: In the primary model, adopting the dietary thresholds produced clear benefit to Aotearoa New Zealand in terms of HALY (1.2 million years [95%UI 1.0-1.5]), and a health system cost saving of $17.9 billion (95%UI 13.6-23.2) over the population life course. HALY gain was at least 1.8 times higher for Māori than non-Māori. The secondary model indicated further gains in HALY for all population groups and health systems costs.

Conclusion: These striking benefits of altering current dietary intakes provide strong evidence of the need for change. Such change requires government commitment to an overarching food strategy in Aotearoa New Zealand to build supportive food environments that enable healthy choices at affordable prices.

Download full-text PDF

Source
http://dx.doi.org/10.26635/6965.6339DOI Listing

Publication Analysis

Top Keywords

dietary thresholds
16
diabetes prevention
12
aotearoa zealand
12
optimised dietary
8
type diabetes
8
health system
8
system cost
8
primary model
8
model considered
8
considered change
8

Similar Publications

Cadmium accumulation in different types of vegetable across China: Dietary exposure risk, and a novel method for determining soil cadmium thresholds.

J Hazard Mater

September 2025

State Key Laboratory of Nutrient Use and Management, Beijing Key Laboratory of Farmland Soil Pollution Prevention and Remediation, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.

Cadmium (Cd) contamination in vegetables poses a potential risk to human health; thus an accurate soil Cd threshold is crucial for early warning to ensure safe production. In this study, a national-scale dataset of Cd contents in agricultural soils and vegetables in China was compiled to assess the dietary exposure risk, and a hybrid approach combining conditional inference trees (CITs) and species sensitivity distribution (SSD) was established to derive soil Cd thresholds. The results showed that amaranth, butterhead lettuce, Chinese cabbage, coriander, and garlic had higher Cd accumulation ability among 34 species studied.

View Article and Find Full Text PDF

Obesity hinders the efficacy of adipose-derived stem cells for knee osteoarthritis by reducing the proportion of DPP4+ stem cells.

Stem Cells Transl Med

July 2025

Department of Joint Surgery and Translational Medical Center for Stem Cell Therapy, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, People's Republic of China.

Osteoarthritis (OA) is the most prevalent and disabling joint disease, while adipose-derived stem cells (ASCs) have emerged as a promising therapeutic option in pre-clinical studies. However, the therapeutic efficacy of ASCs may be influenced by the source of these cells, especially in obese patients. This study compared the effects of intra-articular injections of ASCs from wild-type (WT) and ob/ob (OB) mice.

View Article and Find Full Text PDF

Background Gestational diabetes mellitus (GDM) has been increasingly associated with heightened cardiovascular and thrombotic risk. This study aimed to evaluate hemostatic and metabolic profiles in women with GDM to explore early markers of vascular dysfunction. Methods A retrospective cross-sectional study was conducted among 250 pregnant women diagnosed with GDM between December 2022 and October 2023 at multiple tertiary healthcare facilities in Pakistan.

View Article and Find Full Text PDF

Monitoring the physiology of elephants living in human-production landscapes has become increasingly important for understanding how they cope with various challenges that affect their overall fitness. We assessed physiological stress by measuring faecal glucocorticoid metabolite (fGCM) levels and metabolic states using faecal triiodothyronine (fT3) across three free-ranging Asian elephant populations (one in Central India and two in Northeastern India) whose home ranges encompass varying extents of disturbance in human-production landscapes. We present landscape disturbance metrics to characterize variations in fragmentation and anthropogenic pressures across the study landscapes and use faecal carbon and nitrogen (C/N) ratio as a proxy for dietary quality, with higher C/N values indicating poorer-quality diets.

View Article and Find Full Text PDF

Background: Depression remains a significant global health issue, yet the combined influence of dietary quality and extreme pessimistic thoughts on depressive risk is not fully understood. This study evaluated whether a Balanced Healthy Eating Index (BHEI) and extreme pessimism independently and jointly predict depression in adults.

Materials And Methods: We analyzed data from 17,575 participants aged 18-65 years in the 2007-2018 National Health and Nutrition Examination Survey (NHANES).

View Article and Find Full Text PDF