Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Prior studies have reported that curcumin is inversely associated with reduced markers of atherosclerosis risk, including carotid intima-media thickness (CIMT). This study was designed to assess the effects of curcumin on CIMT and pulse wave velocity (PWV) in diabetic hemodialysis (HD) patients.
Methods: This randomized, double-blinded, placebo-controlled trial was conducted on 39 diabetic HD patients. People were assigned to receive curcumin or placebo (starch) for 24 weeks. Individuals in the curcumin group ( = 26) received 80 mg/day. CIMT and PWV levels were taken at baseline and after 24 weeks of intervention.
Results: After 24 weeks of intervention, curcumin intake did not affect mean levels of left ( = 0.83) and right ( = 0.47) CIMT and maximum levels of left ( = 0.84) and right ( = 0.11) CIMT, and PWV (P = 0.12) compared to the placebo. Furthermore, within-group difference demonstrated a significant reduction in mean levels of PWV ( = 0.01) in the curcumin group. We did not observe any significant change in C-reactive protein (CRP) concentrations after curcumin intake ( = 0.69).
Conclusions: Curcumin intake did not affect mean levels of left and right CIMT and maximum levels of left and right CIMT, PWV, and CRP levels compared to the placebo. Additionally, within-group difference demonstrated a significant reduction in mean levels of PWV in the curcumin group.This trial was registered at www.irct.ir as http://www.irct.ir: IRCT20200527047584N1.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10935569 | PMC |
| http://dx.doi.org/10.4103/ijpvm.ijpvm_55_22 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
fNIRS Biomarkers for Stratifying Poststroke Cognitive Impairment: Evidence From Frontal and Temporal Cortex Activation.
Stroke
September 2025
Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China (H.Z., K.H., Q.G.).
Background: Poststroke cognitive impairment (PSCI) affects 30% to 50% of stroke survivors, severely impacting functional outcomes and quality of life. This study uses functional near-infrared spectroscopy (fNIRS) to assess task-evoked brain activation and its potential for stratifying the severity in patients with PSCI.
Method: A cross-sectional study was conducted at Nanchong Central Hospital between June 2023 and April 2024.
Management of a complex central bile duct injury associated with laparoscopic cholecystectomy: a case report of double hepaticojejunostomy and advanced transhepatic interventional drainage technique.
J Surg Case Rep
September 2025
Department of Hepato-Pancreato-Biliary Surgery, Clinic for General, Visceral and Vascular Surgery, Ernst von Bergmann Klinikum, Charlottenstraße 72, 14467 Potsdam, Germany.
We describe a case of a 64-year-old obese woman with a history of severe acute cholecystitis and choledocholithias who underwent laparoscopic cholecystectomy in our clinic after endoscopic treatment by sphincterotomy and stent insertion. On the first operative day, a significant bile leakage of 400 ml appeared in the drainage. An immediate surgical revision was performed, starting by laparoscopy with conversion to open surgery.
View Article and Find Full Text PDFPrevalence of Sleep-Disordered Breathing and Cheyne-Stokes Respiration in Patients With Atrial Fibrillation.
Rev Cardiovasc Med
August 2025
Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, 113-8421 Tokyo, Japan.
Background: Limited data are available regarding the prevalence of sleep-disordered breathing (SDB), particularly Cheyne-Stokes respiration (CSR), in patients with atrial fibrillation (AF) and left ventricular (LV) systolic dysfunction. Thus, this study aimed to investigate the prevalence of SDB and CSR, as well as the factors associated with these conditions, in patients with AF without LV systolic dysfunction.
Methods: Patients with paroxysmal and non-paroxysmal AF underwent echocardiography and cardiorespiratory polygraphy.
Feasibility of combining tDCS with exercise for increasing physical activity in people with depression.
Front Physiol
August 2025
Butler Hospital, Providence, RI, United States.
Introduction: Physical inactivity and depression are significant public health concerns, often co-occurring and exacerbating one another. Transcranial direct current stimulation (tDCS) has shown promise in enhancing cognitive and affective processes, potentially improving exercise adherence and outcomes in individuals with depressive symptoms. This study aimed to evaluate the feasibility and preliminary within group effects of combining tDCS with an aerobic exercise (AE) intervention to increase physical activity in individuals with elevated depressive symptoms.
View Article and Find Full Text PDFSmaller hippocampal tail volume is associated with plasma CCL11 levels in patients with major depressive disorder.
Psychol Med
September 2025
Department of Psychiatry, https://ror.org/04wjghj95The First Hospital of China Medical University, Shenyang, China.
Background: This study investigates structural abnormalities in hippocampal subfield volumes and shapes, and their association with plasma CC chemokines in individuals with major depressive disorder (MDD).
Methods: A total of 61 patients with MDD and 65 healthy controls (HC) were recruited. All participants underwent high-resolution T1-weighted imaging and provided blood samples for the detection of CC chemokines (CCL2, CCL7, and CCL11).