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Objectives: Compared to lung resections, airway procedures are relatively rare in thoracic surgery. Despite this, a growing number of dedicated airway centres have formed throughout Europe. These centres are characterized by a close interdisciplinary collaboration and they often act as supra-regional referring centres. To date, most evidence of airway surgery comes from retrospective, single-centre analysis as there is a lack of large-scale, multi-institutional databases.
Methods: In 2018, an initiative was formed, which aimed to create an airway database within the framework of the ESTS database (ESTS-AIR). Five dedicated airway centres were asked to test the database in a pilot phase. A 1st descriptive analysis of ESTS-AIR was performed.
Results: A total of 415 cases were included in the analysis. For adults, the most common indication for airway surgery was post-tracheostomy stenosis and idiopathic subglottic stenosis; in children, most resections/reconstructions had to be performed for post-intubation stenosis. Malignant indications required significantly longer resections [36.0 (21.4-50.6) mm] when compared to benign indications [26.6 (9.4-43.8) mm]. Length of hospital stay was 11.0 (4.1-17.3) days (adults) and 13.4 (7.6-19.6) days (children). Overall, the rates of complications were low with wound infections being reported as the most common morbidity.
Conclusions: This evaluation of the 1st cases in the ESTS-AIR database allowed a large-scale analysis of the practice of airway surgery in dedicated European airway centres. It provides proof for the functionality of ESTS-AIR and sets the basis for rolling out the AIR subsection to all centres participating in the ESTS database.
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http://dx.doi.org/10.1093/ejcts/ezae084 | DOI Listing |
Biomater Biosyst
September 2025
ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Introduction: The airway mucosa plays a crucial role in protection and various physiological functions. Current methods for restoring airway mucosa, such as myocutaneous flaps or split skin grafts, create a stratified squamous layer that lacks the cilia and mucus-secreting glands of the native columnar-lined airway. This study examines the application of various injectable biopolymers as active molecules for a potential approach to regenerating laryngeal epithelial tissue.
View Article and Find Full Text PDFFront Allergy
August 2025
Department of Surgery, University of Auckland, Auckland, New Zealand.
Allergic rhinitis (AR) and chronic rhinosinusitis (CRS) are common respiratory conditions that significantly impact patient health and contribute to substantial healthcare burdens. While conventional treatments offer symptom relief, many patients continue to experience persistent symptoms, side effects, or resistance to standard therapies. This highlights the growing need for novel, non-invasive, and sustainable therapeutic strategies to manage chronic airway inflammation.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
September 2025
Department of Otolaryngology Head And Neck Surgery, Far Eastern Memorial Hospital, No. 21, Section 2, Nan-Ya South Road, New Taipei City, Taiwan.
Introduction: Anterior glottic webs are epithelium-covered fibrous tissue formations at the anterior commissure, leading to synechiae between the bilateral vocal folds. They manifest with symptoms ranging from hoarseness to airway obstruction. However, treating anterior glottic webs are challenging due to their high recurrence rates.
View Article and Find Full Text PDFVet Anaesth Analg
August 2025
Department of Anesthesiology and Pain Management, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires, Argentina.
Objective: To evaluate the effect of 5 cmHO positive end-expiratory pressure (PEEP) and end-inspiratory pause (EIP) on airway dead space (V) and its resultant effects on alveolar tidal volume (V) and physiological dead space-to-tidal volume ratio (V/V) in dorsally recumbent anesthetized dogs.
Study Design: Prospective, controlled clinical study.
Animals: Healthy adult dogs (n = 20, > 20 kg) undergoing elective surgery.
Zhonghua Jie He He Hu Xi Za Zhi
September 2025
Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University(Suzhou Dushu Lake Hospital), Suzhou 215000, China.
The TTS(through-the-scope)airway stent is a novel self-expanding nitinol alloy metal stent. Its structure and method of implantation differ significantly from those of the traditional OTW(over-the-wire)stent. In this study, we compared the mechanical properties of the TTS and OTW stents, and both of which were implanted into the tracheas of rabbits to compare the differences in complications caused by these two types of stents.
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