98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s10875-024-01677-x | DOI Listing |
Blood Rev
August 2025
Department of Medicine, Stellenbosch University, Faculty of Medicine and Health Sciences, Tygerberg Campus, South Africa. Electronic address:
Clinicians need a good understanding of available tools to diagnose iron deficiency (ID). Interpretation of commonly used laboratory tests can be challenging due to the dynamic nature of iron homeostasis and concurrent inflammation, which influence results. The misinterpretation of iron studies, inconsistencies in ID diagnostic guidelines, and low awareness of non-anaemic ID may lead to missed diagnoses and opportunities for treatment.
View Article and Find Full Text PDFCan J Ophthalmol
September 2025
Département d'Ophtalmologie et d'Ophtalmologie et d'Oto-Rhino-Laryngologie-Chirurgie Cervico-Faciale, Faculté de Médecine, Université Laval, QC, Canada; Centre Universitaire d'Ophtalmologie, Hôpital du Saint-Sacrement, Centre Hospitalier Universitaire de Québec-Université Laval, QC, Canada.
Objective: To compare the efficacy of different settings in continuous-wave transscleral cyclophotocoagulation (CW-TSCPC).
Design: Prospective, randomized, triple-blind clinical trial in a single tertiary center.
Participants: Adult glaucoma patients who need continuous wave-transscleral cyclophotocoagulation to control intraocular pressure (IOP) or prevent or treat ocular pain/discomfort secondary to increased IOP.
Neuroimage
September 2025
Developing Brain Institute, Children's National Hospital, Washington, D.C. USA; Department of Radiology, The George Washington University School of Medicine and Health Sciences, Washington, D.C. USA; Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, W
The purpose of this study was to compare brain metabolite concentrations between healthy and CHD neonates before and after cardiac surgery. Healthy term newborns and neonates with CHD were recruited prospectively. T-weighted brain images and MRS data were acquired in the cerebellum, right frontal lobe and basal ganglia.
View Article and Find Full Text PDFJ Dent
September 2025
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases; Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.. Electronic address:
Objectives: This retrospective study evaluates alveolar bone remodeling patterns and their association with incisor displacement in adults undergoing clear aligner therapy with premolar extractions for Class II malocclusion correction.
Methods: Cone-beam computed tomography (CBCT) scans of 38 maxillary and 37 mandibular incisors were analyzed. Displacement vectors for four anatomical landmarks (cusp tip [C], root apex [R], root neck midpoint [M], labial cementoenamel junction [L]) were quantified.
Med
August 2025
Joint Academic Rheumatology Program, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece; Centre of New Biotechnologies and Precision Medicine (CNBPM), School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece. Electronic address: p
Background: Pathogenic responses against self and foreign antigens in systemic autoimmunity and infection, respectively, engage similar immunologic components, thus lacking distinguishing diagnostic biomarkers. Herein, we tested whether whole-blood transcriptome analysis discriminates autoimmune from infectious diseases.
Methods: We applied nested cross-validation methodology to tune and validate random forests, k-nearest neighbors, and support vector machines, using a new preprocessing method on 22 publicly available datasets, including 594 patients with a broad spectrum of systemic autoimmune diseases and 615 patients with diverse viral, bacterial, and parasitic infections.