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Stimbiotic supplementation may provide an innovative feed additive solution to accelerate the proliferation of beneficial fiber-degrading bacteria in the distal intestine and the utilization of dietary fiber. Optimal utilization of dietary fiber has multiple benefits for gut health and nutrient utilization. This study was conducted to evaluate the late gestation and lactation performance, the plasma, colostrum, and milk immunoglobulin (IgA, IgG, and IgM) concentrations, and the anti-inflammatory and antioxidant biomarkers in plasma of sows fed with or without a stimbiotic during the late gestation and lactation phase. A total of 40 sows were allocated to two treatment groups: control (CT) with no supplementation or 100 mg/kg stimbiotic (VP), with 20 sows per treatment. Sows were fed the treatment diets from d 85 of gestation to d 28 of lactation. In the results, the average daily weight gain of piglets during lactation was greater from sows fed in the VP group compared to that in the CT group ( < 0.05). The plasma concentrations of IgM at farrowing and IgG at weaning of the sows fed the diet with the stimbiotic supplementation were much higher than those in the CT sows ( < 0.05), respectively. In addition, the dietary stimbiotic increased the concentrations of IgM in the colostrum and of IgA and IgM in the milk at d 14 of lactation ( < 0.05). Plasma concentrations of malondialdehyde (MDA) on d 0 and d 28 of lactation tended to be lower in sows fed the VP diets compared with those of the sows fed the CT diets. Thus, our study indicated that stimbiotic supplementation could improve the daily weight gain of piglets and the immune function of sows in lactation.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10892021 | PMC |
http://dx.doi.org/10.3390/vetsci11020053 | DOI Listing |
Transl Anim Sci
May 2025
Carthage Veterinary Service Ltd., Carthage, IL 62321, USA.
Soybean meal (SBM) contains many bioactive compounds, such as isoflavones, which possess anti-inflammatory and anti-oxidative properties that may provide nutritional intervention to pigs infected with porcine reproductive and respiratory syndrome virus (PRRSv). The disease results in abortions, stillborn piglets, and overall impairs reproductive success in sows. Today, there are no data available on feeding SBM to sows infected with PRRSv to mitigate the negative impacts of PRRSv on sow and litter performance.
View Article and Find Full Text PDFTransl Anim Sci
August 2025
Department of Animal Science, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada.
The objective of this study was to assess how sow and litter performance and nutrient utilization were affected by dietary probiotic supplementation in gestation and lactation diets that contained high levels of canola meal. Seventy-five sows were allotted to one of three treatment diets, starting on d 80 of gestation. The experimental diets included a control diet () composed of corn and soybean meal, or a modified CTRL diet where soybean meal was substituted with 300 g/kg of canola meal, provided either with () or without () product supplementation.
View Article and Find Full Text PDFJ Anim Sci
August 2025
Department of Animal Science, North Carolina State University, Raleigh, NC 27695 USA.
Tryptophan (Trp) is the rate-limiting substrate for the synthesis of serotonin (5-hydroxytryptamine; 5-HT) in the brain, which plays a central role in the regulation of stress sensitivity and feed intake. The objective of this study was to evaluate the effect of oral Trp supplementation to suckling piglets on 5-HT metabolism, growth performance, and behavior during the suckling (14 to 21 d of age) and nursery (21 to 56 d of age) periods, under social mixing stress at weaning. Eighty 14-day-old suckling piglets from 10 sows (8 piglets per litter) were allotted to 2 treatments.
View Article and Find Full Text PDFAnimals (Basel)
August 2025
State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.
Based on an established appropriate substitution level for corn distillers dried grains with solubles (DDGSs) replacing energy-supplying components in the basal diet for pregnant sows, the substitution method was employed to determine the available energy values of corn DDGSs. In Exp. 1, forty pregnant sows (gestation day = 50 ± 5 d; body weight = 220 ± 24.
View Article and Find Full Text PDFJ Anim Sci
January 2025
Key Laboratory of Feed Biotechnology of Ministry of Agriculture and Rural Affairs, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
This study determined the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of crude protein (CP) and amino acids (AA) of corn, barley, and wheat bran in primiparous sows. Four physiological stages of primiparous sows were examined: a gestation stage where sows were restricted-fed, a lactation stage where sows were fed ad libitum, and then two post-weaning stages, an ad libitum-fed phase followed by a restricted-fed phase. A total of 8 primiparous sows fitted with T-cannulas in the distal ileum were assigned to an 8 × 3 Youden square design with 4 diets (corn, barley, wheat bran, and nitrogen [N]-free diet) and three periods, resulting in a total of 6 replicates per treatment.
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