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Objective: To identify the predictors for the achievement of minimal clinically important difference (MCID) in functional status among elderly patients with degenerative lumbar spinal stenosis (DLSS) undergoing lumbar decompression and fusion surgery.
Methods: Patients who underwent lumbar surgery for DLSS and had a minimum of 1-year follow-up were included. The MCID achievement threshold for the Oswestry Disability Index (ODI) was set at 12.8. General patient information and the morphology of lumbar paraspinal muscles were evaluated using comparative analysis to identify influencing factors. Multiple regression models were employed to identify predictors associated with MCID achievement. A receiver operating characteristic (ROC) curve analysis was conducted to determine the optimal cut-off values for predicting functional recovery.
Results: A total of 126 patients (46 males, 80 females; mean age 73.0 ± 5.9 years) were included. The overall rate of MCID achievement was 74.6%. Patients who achieved MCID had significantly higher psoas major muscle attenuation (43.55 vs. 39.23, p < 0.001) and preoperative ODI (51.5 vs. 41.6, p < 0.001). Logistic regression showed that elevated psoas major muscle attenuation (p = 0.001) and high preoperative ODI scores (p = 0.001) were independent MCID predictors. The optimal cut-off values for predicting MCID achievement were found to be 40.46 Hounsfield Units for psoas major muscle attenuation and 48.14% for preoperative ODI.
Conclusion: Preoperative psoas major muscle attenuation and preoperative ODI were reliable predictors of achieving MCID in geriatric patients undergoing lumbar decompression and fusion surgery. These findings offer valuable insights for predicting surgical outcomes and guiding clinical decision-making in elderly patients.
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http://dx.doi.org/10.1186/s12893-024-02356-9 | DOI Listing |
Knee Surg Sports Traumatol Arthrosc
September 2025
Department of Surgery, Division of Orthopaedic Surgery, McMaster University, Hamilton, Ontario, Canada.
Purpose: This analysis evaluated whether logistic regression and machine learning models could predict achievement of the minimal clinically important difference (MCID) for the International Hip Outcome Tool (iHOT-12) and Hip Outcome Score (HOS) at 6 and 12 months following hip arthroscopy.
Methods: Data from the multicenter Femoroacetabular Impingement RandomiSed controlled Trial and its embedded prospective cohort were used. A total of 309 patients (mean ± SD age 34.
Diabetes Obes Metab
September 2025
Graduate School of Physical Education, Myongji University, Yongin, Republic of Korea.
Background: High levels of glycated haemoglobin (HbA1c) in people with type 1 diabetes (T1D) are associated with high mortality and cardiovascular risk. Physical activity is an affordable intervention that is available to most people, but the type and amount of exercise to induce metabolic benefits in T1D are not known with certainty.
Objective: To determine the comparative effectiveness of diverse exercise modes and dosages to influence HbA1c in patients with T1D.
Orthop Surg
September 2025
Sports Medicine Center, West China Hospital, Sichuan University, Department of Orthopedics and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
To manage anterior cruciate ligament (ACL) injury, both remnant-preserving anterior cruciate ligament reconstruction (ACLR) and standard ACLR without remnant preservation are applied. This study aims to systematically evaluate clinical outcomes of remnant-preserving versus standard ACLR techniques by analyzing randomized controlled trials (RCTs). The PubMed, Embase, and Cochrane Library databases were used to identify studies published from January 2000 to November 2024.
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
September 2025
Department of Health and Rehabilitation, Unit of Physiotherapy, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Purpose: The aim of this study was to calculate and provide Patient Acceptable Symptom State (PASS) thresholds, Minimum Clinically Important Difference (MCID), and Minimal Important Change (MIC) values for the ACL-Return to Sport after Injury (ACL-RSI) scale and the Knee Self-Efficacy Scale (K-SES) in patients treated with ACL reconstruction.
Method: Data were extracted from a rehabilitation specific registry, Project ACL. The registry prospectively collects patient-reported outcomes (PROs).
Tuberc Respir Dis (Seoul)
September 2025
Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Republic of Korea.
Background: Although OM-85 may lessen respiratory symptoms and reduce acute exacerbations in chronic obstructive pulmonary disease (COPD), its overall effectiveness remains incompletely proven.
Methods: This prospective, observational, single-arm study was conducted at four university hospitals in South Korea from June 2022 to December 2023. Adults with spirometry-confirmed COPD who were prescribed OM-85 were enrolled and followed for six months (3-months treatment, 3-months observation).