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The objective of this study was to improve water solubility of the rice protein (RP) by forming complexes with anionic polysaccharides, such as sodium alginate (SA) and xanthan gum (XG). In addition, utilization of the RP complexes as an emulsifier was evaluated. The prepared RP-SA or RP-XG complexes were analyzed by measuring their particle size, ζ-potential, and water solubility as well as by confocal laser scanning microscopy. The formation of a complex between RP-SA and RP-XG improved the water solubility and dispersibility of RP over a wide range of pH values (3, 5, 7, and 9). Confocal fluorescence images showed that the aggregation of RP molecules was prevented by the formation of complexes between RP and polysaccharides. When soybean oil-in-water emulsions were prepared with complexes, RP-SA (ratio 4:1) and RP-XG(ratio 4:1) complex-stabilized emulsions were stable for 4 weeks of storage.
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http://dx.doi.org/10.1007/s10068-023-01350-w | DOI Listing |
J Mater Chem B
September 2025
Major in Bionano Engineering, School of Bio-Pharmaceutical Convergence, Hanyang University, Ansan, 155-88, Republic of Korea.
Membrane proteins are essential bio-macromolecules involved in numerous critical biological processes and serve as therapeutic targets for a wide range of modern pharmaceuticals. Small amphipathic molecules, called detergents or surfactants, are widely used for the isolation and structural characterization of these proteins. A key requirement for such studies is their ability to maintain membrane protein stability in aqueous solution, a task where conventional detergents often fall short.
View Article and Find Full Text PDFJ Mater Chem B
September 2025
State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, College of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Adenosine triphosphate (ATP) is a critical biomolecule in cellular energy metabolism, with abnormal levels in the bloodstream linked to pathological conditions such as ischemia, cancer, and inflammatory disorders. Accurate and real-time detection of ATP is essential for early diagnosis and disease monitoring. However, conventional biochemical assays and other techniques suffer from limitations, including invasive sample collection, time-consuming procedures, and the inability to provide dynamic, monitoring.
View Article and Find Full Text PDFTurk J Pharm Sci
September 2025
University of Maryland, Department of Pharmaceutical Sciences, Baltimore, USA.
Objectives: Norvir oral powder [ritonavir (RTV)] employs polyvinylpyrrolidone/vinyl acetate as the polymer to formulate an amorphous solid dispersion. Its oral absolute bioavailability is 70% in the fasted state, and it has negative food effects. The aim of this study was to perform in vitro dissolution of Norvir powder and Wagner-Nelson deconvolution of data under fasted, moderate fat, and high fat conditions in order to elucidate the relevance of dissolution testing.
View Article and Find Full Text PDFTurk J Pharm Sci
September 2025
Chandigarh College of Pharmacy, Chandigarh Group of Colleges, Landran, Punjab.
Objectives: Lycopene is a powerful antioxidant with diverse health benefits. However, it belongs to the Biopharmaceutics Classification System II; thus, it depicts poor water solubility and dissolution. Its lipophilic nature hinders the bioavailability of this drug.
View Article and Find Full Text PDFWater Res
August 2025
State Key Laboratory of Environmental Aquatic Chemistry, Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Phosphorus is recognized as a major pollutant in municipal and domestic wastewater, but the effective removal of organic phosphorus (OP) using conventional wastewater treatment technologies is difficult. Herein, a novel visible light-enhanced Ti electrocoagulation (EC) technology was proposed for the removal of OP using 2-amino-ethyl phosphonic acid (AEP) as a model compound to elucidate the removal efficiency and mechanisms. The results showed that the irradiation under visible light (670 Lux) effectively enhanced the removal of AEP by Ti EC.
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