Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
MicroRNAs (miRNAs) are small noncoding RNAs that oversee gene modulation. They are integral to cellular functions and can migrate between species, leading to cross-kingdom gene suppression. Recent breakthroughs in helminth genome studies have sparked curiosity about helminth RNA regulators and their ability to regulate genes across species. Growing data indicate that helminth miRNAs have a significant impact on the host's immune system. Specific miRNAs from helminth parasites can merge with the host's miRNA system, implying that parasites could exploit their host's regulatory machinery and function. This review highlights the role of cross-kingdom helminth-derived miRNAs in the interplay between host and parasite, exploring potential routes for their uptake, processing, and consequences in host interaction.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pt.2023.12.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Combined Fusarium Crown Rot and Drought Stress Leads to Overlapping and Unique Proteomic Responses in Wheat.
Phytopathology
September 2025
College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.
Fusarium crown rot (FCR) is a soilborne disease that occurs in many cereal-growing regions in the world. An association between FCR development and drought stress has long been known. The FCR symptoms are pronounced under drought stress in both fields and controlled environments.
View Article and Find Full Text PDFNuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation.
Nucleic Acids Res
September 2025
Department of Biosciences & Bioengineering, IIT Bombay, Mumbai 400076, India.
Embryonic stem cells (ESCs), which are susceptible to DNA damage, depend on a robust and highly efficient DNA damage response (DDR) mechanism for their survival. However, the implications of physical force-mediated DNA damage on ESC fate remain unclear. We show that stiffness-dependent spreading of mouse ESCs (mESCs) induces DNA damage through nuclear compression, with DNA damage causing differentiation through Lamin A/C.
View Article and Find Full Text PDFMetabolic consequences and gut microbiome alterations in rats consuming pork or a plant-based meat analogue.
Food Funct
September 2025
Laboratory for Animal Nutrition and Animal Product Quality (LANUPRO), Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, B-9000, Ghent, Belgium.
It is unknown how human health is affected by the current increased consumption of ultra-processed plant-based meat analogues (PBMA). In the present study, rats were fed an experimental diet based on pork or a commercial PBMA, matched for protein, fat, and carbohydrate content for three weeks. Rats on the PBMA diet exhibited metabolic changes indicative of lower protein digestibility and/or dietary amino acid imbalance, alongside increased mesenteric (+38%) and retroperitoneal (+20%) fat depositions despite lower food and energy intake.
View Article and Find Full Text PDFEconomic burden and health-related quality of life in Chinese patients with mycosis fungoides and Sézary syndrome.
Cancer Pathog Ther
September 2025
Department of Hematology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Background: The health-related quality of life (HRQoL), economic burden, and diagnostic and treatment status of Chinese patients with mycosis fungoides (MF) and Sézary syndrome (SS) remain largely unknown. This study assessed patient characteristics, HRQoL, and economic burden among Chinese patients with MF and SS through a cross-sectional survey.
Methods: Eligible patients were aged ≥18 years with a pathologically confirmed diagnosis of MF or SS and were either currently receiving or had received disease-specific treatment within the past year.