Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Cryptococcal pneumonia is identified as a fungal infection of the lungs, with and as the most common culprits.  primarily affects immunocompromised individuals while infections occur mostly in immunocompetent hosts. We present a 76-year-old male on ibrutinib due to a history of chronic lymphocytic leukemia who had multiple hospitalizations for pneumonia and was later diagnosed with cryptococcal pneumonia through positive bronchoalveolar lavage fungal culture and lymph node biopsy.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681705PMC
http://dx.doi.org/10.7759/cureus.47884DOI Listing

Publication Analysis

Top Keywords

cryptococcal pneumonia
12
pneumonia patient
4
patient tyrosine
4
tyrosine kinase
4
kinase inhibitor
4
inhibitor therapy
4
therapy common
4
common it?
4
it? cryptococcal
4
pneumonia identified
4

Similar Publications

Rationale: Cryptococcal meningitis is caused by Cryptococcus neoformans and Cryptococcus gattii, predominantly affects immunocompromised host. Resistance to amphotericin B poses therapeutic challenges, especially in immunocompetent individuals, where evidence is scarce.

Patient Concerns: This study reports a case of an old immunocompetent male diagnosed with amphotericin B-resistant C neoformans meningitis.

View Article and Find Full Text PDF

Background: Cryptococcal disease is considered a major cause of morbidity in individuals with HIV in resource-limited settings. The long-term effects of COVID-19 and cryptococcal coinfection among people living with HIV (PLWHIV) have not been thoroughly investigated. This study examined the incidence of cryptococcosis among HIV-positive individuals following COVID-19.

View Article and Find Full Text PDF

Background: Tuberculosis (TB) and human immunodeficiency virus (HIV) infection are infectious diseases that pose serious threats to human health. TB and HIV can interact to promote the progression of diseases. This study aims to provide basic evidence for the formulation of disease prevention and control strategies.

View Article and Find Full Text PDF

Background: Pulmonary fungal infections are becoming increasingly prevalent, particularly among immunocompromised patients. Traditional culture-based and serological diagnostic methods exhibit low sensitivity and prolonged turnaround times (TATs), highlighting the need for more efficient diagnostic approaches. This study aims to evaluate the diagnostic performance of metagenomic third-generation sequencing (mTGS) using the Oxford Nanopore platform (Oxford Nanopore Technologies) for the detection of fungal pathogens in lower respiratory tract infections, and to compare its effectiveness with conventional diagnostic methods.

View Article and Find Full Text PDF

Background: Patients with inflammatory bowel disease may develop infective pneumonia after using tumor necrosis factor-α inhibitors(TNFis). Due to the limitations of clinical trials, the occurrence of infective pneumonia in patients with inflammatory bowel disease using tumor necrosis factor-α(TNF-α) inhibitors remains uncertain. This article primarily explores the relationship between TNF-α inhibitors and adverse events(AEs) related to infective pneumonia in the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database.

View Article and Find Full Text PDF