Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
•Sebaceous carcinoma is rare on the vulva and uncommonly associated with HPV.•Pregnancy may play a role in onset or exacerbation of HPV-associated vulvar cancers.•Treatment of vulvar sebaceous carcinoma is local excision and sentinel lymph node dissection with close follow-up.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641161 | PMC |
| http://dx.doi.org/10.1016/j.gore.2023.101298 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Prognosis of HPV-independent, p53-wild-type vulvar squamous cell carcinoma: A systematic review and meta-analysis.
Gynecol Oncol
September 2025
Pathology Unit, Department of Oncology, ASST Sette Laghi, Varese, Italy; Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy. Electronic address:
Background: Vulvar squamous cell carcinoma (VSCC) is subdivided into TP53-mutant (TP53) and HPV-associated (HPV). In recent years, a third group unrelated to TP53 mutation or HPV-association (TP53/HPV) has emerged. However, its prognosis is unclear.
View Article and Find Full Text PDFAssessment of Nectin4-expression in vulvar squamous cell carcinomas (VSCC): correlation with HPV-associated and HPV-independent molecular subtypes.
Hum Pathol
September 2025
Division of Gynecologic, Breast and Perinatal Pathology, Institute of Pathology, University Hospital Leipzig, Germany.
Background: The development of antibody-drug conjugates (ADC) for cancer treatment has achieved promising results in different solid tumors and targets. Enfortumab-Vedotin (EV), a humanised anti-Nectin4-IgG1 monoclonal antibody linked to the microtubule-disrupting agent monomethyl auristatin E (MMAE), is an FDA-approved Nectin4-directed ADC for the treatment of locally advanced or metastatic pre-treated urothelial cancer. Targeted therapy with EV requires the expression of Nectin4 within the tumor cells.
View Article and Find Full Text PDFEmerging nanotherapeutics for HPV-associated cancers: current advances, challenges, and future directions.
Discov Oncol
August 2025
Department of Biotechnology, School of Bio Sciences and Technology (SBST), Vellore Institute of Technology, Vellore, 632014, India.
Human Papillomavirus or HPV are viruses belonging to the family Papillomaviridae, these have double-stranded circular DNA. HPV is among the most common sexually transmitted infections which affect over 50% of the adult population. It is also responsible for approximately 5% of total cancer cases.
View Article and Find Full Text PDFElevated Risk of HPV-Associated Oropharyngeal Cancers in Husbands of Women With Anogenital Cancer.
Cancer Rep (Hoboken)
September 2025
Molecular Genetic Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Introduction: Human papillomavirus (HPV) infection is associated with tonsillar and base-of-tongue squamous cell carcinomas (TSCC/BOTSCC). We evaluated the relative risk (RR) of TSCC/BOTSCC in the husbands of women with anogenital cancer using the Swedish family database.
Methods: The Swedish family database includes 3.
HPV negative conversion following Hiporfin PDT for HPV associated HSIL in the female lower reproductive tract.
Sci Rep
August 2025
Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Currently, there is no relevant literature specifically discussing the human papillomavirus (HPV) negative conversion rate following Hiporfin photodynamic therapy (PDT) in HPV-associated high-grade squamous intraepithelial lesion (HSIL) of the female lower reproductive tract. Our study aims to fill this gap. Prospective study of 91 patients aged 37.
View Article and Find Full Text PDF