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http://dx.doi.org/10.23736/S2784-8671.23.07602-8 | DOI Listing |
Front Med (Lausanne)
August 2025
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Background: Psoriasis is associated with increased cardiovascular risk, possibly mediated by inflammation-induced hemostatic dysregulation and hypercoagulability. However, these changes are often difficult to detect with conventional markers.
Objectives: To assess hypercoagulability in patients with psoriasis using the Overall Hemostatic Potential (OHP) test, a global integrative test for coagulation and fibrinolysis.
J Dermatol
September 2025
Department of Dermatology, SMG-SNU Boramae Medical Center, Seoul, Korea.
Patients with psoriasis experience significantly higher cardiovascular morbidity compared to the general population. Although certain psoriasis treatments may confer cardioprotective effects, current clinical guidelines addressing treatment continuation following major adverse cardiovascular events (MACE) are lacking. Therefore, we conducted a retrospective cohort study using Korean health insurance data (January 2008-October 2021) to examine treatment modifications after MACE in patients with psoriasis.
View Article and Find Full Text PDFExp Dermatol
September 2025
Department of Plastic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
This study utilised NHANES data from 2003 to 2006 and 2009 to 2014 to explore the association between the non-high-density lipoprotein to high-density lipoprotein cholesterol ratio (NHHR) and psoriasis. A total of 15 437 U.S.
View Article and Find Full Text PDFItal J Dermatol Venerol
September 2025
Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Atopic dermatitis is the most common chronically or chronically relapsing inflammatory skin disease, characterized by intense pruritus, eczematous lesions, and a significant disease burden. Emerging evidence in recent years suggests that atopic dermatitis and the associated chronic systemic inflammation have health implications beyond the skin. For psoriasis, another chronic inflammatory skin disease, the association with cardiovascular diseases (CVDs) is well-established.
View Article and Find Full Text PDFCureus
August 2025
Department of Pathology, Mahatma Gandhi Memorial Medical College, Indore, IND.
Introduction Psoriasis is a chronic, immune-mediated inflammatory skin disease with systemic manifestations. Among its significant comorbidities, metabolic syndrome (MS) - a constellation of obesity, hypertension, dyslipidemia, and insulin resistance - has gained recognition due to its association with increased cardiovascular risk and reduced life expectancy. Chronic systemic inflammation, shared immunological pathways, and elevated pro-inflammatory cytokines are thought to underlie this association.
View Article and Find Full Text PDF