Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-023-02834-zDOI Listing

Publication Analysis

Top Keywords

correction fgf19
4
fgf19 fgfr4
4
fgfr4 promotes
4
promotes progression
4
progression gallbladder
4
gallbladder carcinoma
4
carcinoma autocrine
4
autocrine pathway
4
pathway dependent
4
dependent gpbar1-camp-egr1
4

Similar Publications

Background: Some studies have established a link between gut microbiota, inflammatory proteins, and inflammatory dermatoses. However, the mediating role of inflammatory proteins in the gut-skin axis remains unclear.

Methods: Data on inflammatory proteins and gut microbiota were drawn from the GWAS catalog and MiBioGen consortium, with inflammatory skin disease data provided by the FinnGen consortium.

View Article and Find Full Text PDF

Background: Diabetic sensorimotor polyneuropathy (DSPN) is often asymptomatic and remains undiagnosed. The ability of clinical and anthropometric variables to identify individuals likely to have DSPN might be limited. Here, we aimed to integrate protein biomarkers for reliably predicting present DSPN.

View Article and Find Full Text PDF

The role of FGF15/FGF19 in the development of the central nervous system, eyes and inner ears in vertebrates.

Tissue Cell

December 2024

Área de Biología Celular, Facultad de Ciencias, Universidad de Extremadura, Avda. de Elvas s/n, Badajoz 06071, Spain.

Fibroblast growth factor 19 (FGF19), and its rodent ortholog FGF15, is a member of a FGF subfamily directly involved in metabolism, acting in an endocrine way. During embryonic development, FGF15/FGF19 also functions as a paracrine or autocrine factor, regulating key events in a large number of organs. In this sense, the Fgf15/Fgf19 genes control the correct development of the brain, eye, inner ear, heart, pharyngeal pouches, tail bud and limbs, among other organs, as well as muscle growth in adulthood.

View Article and Find Full Text PDF

Causal effects of circulating inflammatory proteins on oral phenotypes: Deciphering immune-mediated profiles in the host-oral axis.

Int Immunopharmacol

January 2025

Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials

Article Synopsis
  • Oral health can indicate larger health issues, with inflammatory proteins playing a key role in linking oral and systemic health.
  • A study used genetic data to analyze the causal effects of 91 inflammatory proteins on 17 oral traits, identifying 5 proteins that significantly correlated with specific oral conditions.
  • These findings enhance our understanding of how immune responses are linked to oral health and could inform future clinical practices and public health strategies.
View Article and Find Full Text PDF

Objectives: Carpal tunnel syndrome (CTS) and certain inflammatory cytokines have been linked in observational studies; however, the exact causative linkages remain unknown. The purpose of this study is to investigate any possible link between the onset of CTS and 91 inflammatory cytokines.

Methods: A two-sample bidirectional Mendelian randomization (MR) approach was used in this investigation.

View Article and Find Full Text PDF