Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Insect pests and phytopathogens significantly impact crop yield and quality. The fall armyworm (FAW) and the phytopathogen cause substantial economic losses in crops like barley and wheat. However, the entomopathogen shows limited efficacy against FAW, and its antiphytopathogenic activities against remain unclear. Here, dual RNA sequencing was performed to identify differentially expressed genes in -infected FAW larvae. We found that the gene was significantly upregulated at 36 and 48 h post-infection. encodes a serine-carboxyl protease and is mainly expressed in blastospores and hyphae. Overexpression of in ARSEF2860 enhanced virulence against and FAW larvae and inhibited growth. The recombinant BbAorsin protein induced apoptosis and necrosis in FAW hemocytes and inhibited spore germination. These findings shed light on transcriptomic mechanisms governing insect-pathogen interactions, which could aid in developing dual-functional entomopathogens and anti-phytopathogens.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.jafc.3c02356 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mechanistic insights into DNA binding by BD1 of the TAF1 tandem bromodomain module.
Biochem J
September 2025
Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur Campus, Mohanpur, 741246 Nadia, West Bengal, India.
Transcription initiation factor TFIID subunit 1 (TAF1) is a pivotal component of the TFIID complex, critical for RNA polymerase II-mediated transcription initiation. However, the molecular basis by which TAF1 recognizes and associates with chromatin remains incompletely understood. Here, we report that the tandem bromodomain module of TAF1 engages nucleosomal DNA through a distinct positively charged surface patch on the first bromodomain (BD1).
View Article and Find Full Text PDFMechanistic study on the inhibition of triple-negative breast cancer progression by LncRNA TFAP2A-AS1 through the regulation of miR-6892/PHGDH.
Inflamm Res
September 2025
Department of General Surgery, Beijing Anzhen Hospital, Capital Medical University, No.2 Anzhen Road, Chaoyang District, Beijing, 100029, China.
Background: The roles of long non-coding RNAs (lncRNAs) in the progression of various human tumors have been extensively studied. However, their specific mechanisms and therapeutic potential in Triple-Negative Breast Cancer (TNBC) remain to be fully elucidated.
Materials And Methods: The qRT-PCR assay was utilized to assess the relative mRNA levels of TFAP2A-AS1, PHGDH, and miR-6892.
Clinical Evaluation of Initial Experiences With the Qualitative Dual Detection of Core Antigen and Antibodies Immunoassay for Hepatitis C Virus Screening Test.
Hepatol Res
September 2025
Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Izunokuni, Shizuoka, Japan.
Aim: Hepatitis C virus (HCV) infection remains a global health concern. Although the World Health Organization (WHO) proposed a strategy to eliminate HCV by 2030, Japan faces challenges owing to limited access and insufficient support for high-risk populations. Previously, HCV diagnoses required a two-step process, delaying results and increasing costs.
View Article and Find Full Text PDFDevelopment of a TaqMan probe-based dual real time PCR assay for the identification of NADC34-like PRRSV.
Vet Anim Sci
December 2025
Enzyme Engineering Research Center of Shaanxi Province, Xi'an 710600, China.
Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus that induces reproductive disorders in sows and respiratory diseases in growing pigs. Recently, the NADC34-like strain of PRRSV has become more prevalent, with outbreaks occurring across pig farms in China. However, a reliable diagnostic method for the clinical detection of this strain has been absent.
View Article and Find Full Text PDFpredicts poor prognosis and modulates immune infiltration in gastric cancer: a TCGA-based bioinformatics study.
Front Genet
August 2025
Department of Gastrointestinal and Hernia Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, China.
Background: Gastric cancer (GC) is a leading cause of cancer-related mortality; however, biomarkers predicting its immunotherapy resistance remain scarce. Vascular cell adhesion molecule ()-, an immune cell adhesion mediator, is implicated in tumor progression; however, its prognostic and immunomodulatory roles in GC remain unclear.
Methods: In this study, we analyzed expression and its clinical relevance in GC using RNA-sequencing data from The Cancer Genome Atlas.