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http://dx.doi.org/10.1093/ofid/ofad423 | DOI Listing |
Br J Anaesth
September 2025
Department of Anesthesiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China. Electronic address:
Br J Anaesth
September 2025
Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai, China. Electronic address:
Eur Heart J Open
July 2025
Amsterdam UMC Location University of Amsterdam, Department of Experimental Vascular Medicine, Amsterdam Cardiovascular Sciences, Meibergdreef 9, 1105AZ Amsterdam, Netherlands.
Aims: Calcific aortic valve disease is the most common valvular heart disease characterized by an inflammatory response in the leaflets followed by fibro-calcific remodelling of valvular interstitial cells (VICs). Lipoprotein(a) [Lp(a)] is a well-recognized risk factor for CAVD, however the role of metabolism in driving Lp(a)-induced inflammation remains largely elusive. Therefore, we aim to investigate the role of Lp(a) in driving inflammatory and metabolic changes in VICs and examine how alterations in cellular metabolism can alter their inflammatory phenotype.
View Article and Find Full Text PDFOral Dis
September 2025
Geriatrics and Long-Term Care Department, Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar.
J Neurol Sci
August 2025
Department of Neurology III, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China. Electronic address:
This comment letter responds to Edward H. Reynolds' comprehensive review on folate, vitamin B12, one‑carbon metabolism, and nervous system health. While commending the review's insights into the potential neurological harms of excess folic acid, especially with vitamin B12 deficiency, we expand on several critical areas.
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