Combination Therapy of Ivabradine with Procainamide for the Management of Pediatric Postoperative Junctional Ectopic Tachycardia.

J Innov Card Rhythm Manag

Division of Pediatric Cardiology, Department of Pediatrics, Norton Children's Hospital, University of Louisville School of Medicine, Louisville, KY, USA.

Published: July 2023


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Article Abstract

Pediatric postoperative junctional ectopic tachycardia (JET), although usually self-limited, may lead to significant morbidity and mortality. Anti-arrhythmic medications are often necessary to restore atrioventricular synchrony when non-pharmacological measures fail. Multiple drugs have been described for the management of postoperative JET, with enteral ivabradine being the latest addition. While safe administration of ivabradine has been described in combination with other anti-arrhythmics (amiodarone, flecainide), no study has described the use of ivabradine in conjunction with intravenous procainamide for the management of postoperative JET. Our case report describes the safe use of ivabradine and procainamide combination therapy in a young patient.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364659PMC
http://dx.doi.org/10.19102/icrm.2023.14075DOI Listing

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