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The determination of histamine in Greek foods that should potentially be avoided during a "low histamine diet" is reported herein. Cation exchange chromatography combined to selective post column derivatization proved to be an excellent tool for this type of analysis as well, offering accurate results following minimal sample preparation. Tomato-, eggplant- and spinach-related products have been successfully analyzed and were all found to contain histamine. Higher amounts were quantified in eggplants, eggplant salads and spinach in the range of 15.4-34.2 mg kg and lower in fresh tomatoes and related products (0.8-10.6 mg kg). The method is capable of determining as low as 0.5 mg kg histamine without matrix effects, with percent recoveries ranging between 87 and 112% (tomatoes and related products), 95 and 119% (eggplants and related products) and 90 and 106% (fresh and frozen spinach).
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http://dx.doi.org/10.3390/foods11203234 | DOI Listing |
Allergol Immunopathol (Madr)
September 2025
Department of Pulmonary Medicine, Rajasthan Hospital, Jaipur, India.
Saline nasal irrigation provides symptom relief in allergic rhinitis (AR), but the optimal saline concentration remains uncertain. The comparative efficacy of 3% hypertonic saline nasal irrigation (HSNI) versus 0.9% isotonic saline is still debated.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Animal Science, Federal University of Paraná, Curitiba, Paraná, Brazil.
This study aimed to assess the impact of yeast beta-1,3/1,6-glucans (BG) on apparent digestibility coefficients (ADC) of nutrients, intestinal fermentative metabolites, fecal microbiota profile, and immune and antioxidant variables in puppies before and after surgical challenge. Two treatments were evaluated: control, without, and test, with oral supplementation of 65 mg/kg body weight/day of purified BG from Saccharomyces cerevisiae for 120 days. For this, 16 growing Beagle dogs were distributed in a completely randomized design (n = 8/treatment).
View Article and Find Full Text PDFJ Ethnopharmacol
September 2025
Department of Anesthesiology and Perioperative Medicine, Affiliated First Hospital of Ningbo University, Ningbo 315010, China; Key Laboratory of Anesthesiology and Pain Medicine, Ningbo Hospital of Zhejiang University, Ningbo 315010, China. Electronic address:
Ethnopharmacological Relevance: Ligusticum chuanxiong (CX) is a traditional Chinese medicine with diverse effects, such as anti-inflammatory, antioxidant, neuroprotective, anti-nociceptive, and anticancer properties. It has been used in clinical applications with satisfying therapeutic effects. However, the underlying mechanism that contributes to the anti-pruritic effects remains to be comprehensively investigated.
View Article and Find Full Text PDFJ Food Prot
September 2025
University of Sassari, Department of Veterinary Medicine, Via Vienna 2, 07100 Sassari, Italy. Electronic address:
The presence of Histamine is generally used as an indicator of the good manufacturing practice and of the preservation state of canned tuna. This product is widely used as an ingredient in the catering trade with frequent incorrect storage conditions and likely postprocessing contamination causing Histamine production. In this study, we have applied a rapid ELISA screening method for the quantitative determination of Histamine in canned tuna used as an ingredient in the catering trade.
View Article and Find Full Text PDFChitin and chitosan, characterized by their extensive applications, abundant availability, and low cost, have been demonstrated to modulate immune responses. Mast cells (MCs) are important innate immune cells, and few studies on the regulation of MCs by chitin and chitosan were conducted. The key receptor Mas-related G protein-coupled receptor X2 (MRGPRX2), highly expressed in MCs, is involved in drug pseudo-allergic responses and several chronic diseases by mediating MC activation.
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