Modulation of the immune system of chickens a key factor in maintaining poultry production-a review.

The awareness of poultry production safety is constantly increasing. The safety of poultry production is defined as biosecurity and the health status of birds. Hence the constant pursuit of developing new strategies in this area is necessary. Biosecurity is an element of good production practices that ensures adequate hygiene and maintaining the health status of poultry production. Poultry production is the world leader among all livestock species. Producers face many challenges during rearing, which depend on the utility type, the direction of use, and consumer requirements. For many years, the aim was to increase production results. Increasing attention is paid to the quality of the raw material and its safety. Therefore, it is crucial to ensure hygiene status during production. It can affect the immune system's functioning and birds' health status. Feed, water, and environmental conditions, including light, gases, dust, and temperature, play an essential role in poultry production. This review aims to look for stimulators and modulators of the poultry immune system while affecting the biosecurity of poultry production. Such challenges in current research by scientists aim to respond to the challenges posed as part of the One Health concept. The reviewed issues are a massive potential for an innovative approach to poultry production and related risks as part of the interaction of the animal-human ecosystem.