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Aims: We examined the association between television (TV) viewing time and all-cause and cardiovascular disease (CVD) mortality among Japanese adults with and without a history of stroke or myocardial infarction (MI).
Methods: In the Japan Collaborative Cohort Study, 76,572 participants (851 stroke survivors, 1,883 MI survivors, and 73,838 persons without a history of stroke or MI), aged 40-79 years at baseline (1988-1990), completed a lifestyle, diet, and medical history questionnaire, and were followed up regarding mortality until 2009. The Cox proportional hazard model was used to calculate the multivariable-adjusted hazard ratios (HRs) with 95% confidence intervals (CIs) of all-cause and CVD mortality.
Results: During the 19.3-year median follow-up period, 17,387 deaths were documented. TV viewing time was positively associated with all-cause and CVD mortality regardless of stroke or MI history. The multivariable-adjusted HRs of all-cause mortality with 95% CIs for TV viewing time of 3-4.9 h, 5-6.9 h, and ≥ 7 h were 1.18 (0.95-1.48), 1.12 (0.86-1.45), and 1.61 (1.12-2.32) for stroke survivors; 0.97 (0.81-1.17), 1.40 (1.12-1.76), and 1.44 (1.02-2.03) for MI survivors; and 1.00 (0.96-1.03), 1.07 (1.01-1.12), and 1.22 (1.11-1.34) for persons without a history of stroke or MI, respectively, compared with <3 h.
Conclusions: Prolonged TV viewing time was associated with higher risks of all-cause and CVD mortality in stroke or MI survivors and in persons without a history of them. It may be recommended to reduce sedentary time for stroke or MI survivors, independent of the level of physical activity.
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http://dx.doi.org/10.5551/jat.63959 | DOI Listing |
Ther Innov Regul Sci
September 2025
Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Introduction: During the COVID-19 pandemic, regulatory and market access actions were taken to expedite the market entry of COVID-19 medicines. This study aims to (i) capture multi-stakeholder views on these actions, and (ii) provide recommendations for future-proofing routine and health-emergency frameworks.
Methods: Semi-structured interviews were conducted with policy makers/advisors (i.
Infant Behav Dev
September 2025
Center for Mind and Brain, University of California, Davis, USA; Department of Psychology, University of California, Davis, USA.
At the beginning of the twenty-first century, the primary view of infant visual attention development focused on a transition across the first postnatal year from being stimulus-driven to goal-driven, reflecting a broader shift from subcortical to cortical control. This perspective was supported by decades of infant looking-time studies. However, our understanding of infant attention has significantly evolved over the past 25 years, shaped by both theoretical advancements and new technological and methodological tools.
View Article and Find Full Text PDFPhysiotherapy
June 2025
PenCRU (Peninsula Childhood Disability Research Unit), Department of Health & Community Sciences, University of Exeter Medical School, University of Exeter, St Luke's Campus EX1 2LU, UK. Electronic address:
Objectives: Children and young people with complex neurodisability (CYPCN) are at high risk of respiratory illness, frequent hospital admissions and premature death. This study aimed to test the acceptability and feasibility of Breathe-Easy, a novel night-time postural intervention to improve respiratory health in CYPCN.
Design: Case series design incorporating a pre-post interventional study and qualitative study.
Palliat Med
September 2025
Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, Cicely Saunders Institute, King's College London, London, UK.
Background: A dearth of evidence exists on how to include children and young people in palliative care research.
Aim: We aimed to identify successful practices in involvement, recruitment and data collection with children and young people with life-limiting illness in research.
Design: We synthesised methods from five primary studies from three geographical regions in which children with life-limiting conditions were recruited and interviewed.
Mol Psychiatry
September 2025
Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Iron-the most abundant magnetic brain substance-is essential for many biological processes, including dopamine and myelin synthesis. Quantitative susceptibility mapping (QSM) MRI has recently linked altered subcortical magnetic susceptibility (χ) to schizophrenia. Since χ is increased by iron and decreased by myelin, abnormal levels of either could underlie these QSM differences.
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