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http://dx.doi.org/10.1016/j.jinf.2023.05.014 | DOI Listing |
Pestic Biochem Physiol
November 2025
National Key Laboratory of Green Pesticide, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China. Electronic address:
Entomopathogenic fungi can precisely inhibit the cellular and humoral immune responses of host insects by secreting effector proteins, allowing them to overcome the innate immune barriers of their hosts. Nodule formation is an immune response primarily mediated by insect hemocytes, which can rapidly and efficiently capture invading pathogenic fungi in the hemocoel. However, the molecular mechanisms by which fungi inhibit insect nodule formation through the secretion of effector proteins remain unclear.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Yantai Academy of Agricultural Sciences, Yantai 265500, China. Electronic address:
The diamide insecticide cyantraniliprole (CYA) and the triazole fungicide difenoconazole (DIF) are frequently co-detected in bee-related matrices. However, the interactive effects of these compounds on honey bee (Apis mellifera L.) physiology remain insufficiently elucidated.
View Article and Find Full Text PDFInsect Biochem Mol Biol
September 2025
Laboratory of Molecular Entomology and Bee Pathology (L-MEB), Department of Biochemistry and Microbiology, Faculty of Sciences, Ghent University, Ghent, Belgium. Electronic address:
This study maps the surfaceome of Apis mellifera hemocytes, the protagonist cells in honey bee cellular immunity. The surfaceome, proteins expressed at the cell surface, is crucial as it determines how cells interact with their microenvironment. Through a combination of proteomic and transcriptomic analyses, 1142 genes encoding cell surface proteins were identified, revealing a high level of diversity.
View Article and Find Full Text PDFMol Immunol
September 2025
Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, 221005, India. Electronic address:
The innate immune response is a double-edged sword in insects, comprising the humoral and cellular mechanisms to fight and eliminate pathogens. The humoral response is achieved by the production of antimicrobial peptides, which are secreted in the hemolymph. The cellular responses are mediated by phagocytosis, encapsulation and melanization.
View Article and Find Full Text PDFAm J Clin Nutr
September 2025
COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address:
Circulating levels of 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid (CMPF), a metabolite derived from dietary furan fatty acids primarily found in marine food sources, have long been recognized as biomarkers for fish intake. However, elevated CMPF levels are also observed in patients with type 2 diabetes or chronic kidney disease and in healthy people associated with a reduced infection risk, suggesting potential bioactive roles in metabolism and immune function. Yet, the possible causal mechanisms behind these associations are unknown.
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