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Purpose: To design and implement a multi-coil (MC) array for B field generation for image encoding and simultaneous advanced shimming in a novel 1.5T head-only MRI scanner.
Methods: A 31-channel MC array was designed following the unique constraints of this scanner design: The vertically oriented magnet is very short, stopping shortly above the shoulders of a sitting subject, and includes a window for the subject to see through. Key characteristics of the MC hardware, the B field generation capabilities, and thermal behavior, were optimized in simulations prior to its construction. The unit was characterized via bench testing. B field generation capabilities were validated on a human 4T MR scanner by analysis of experimental B fields and by comparing images for several MRI sequences acquired with the MC array to those acquired with the system's linear gradients.
Results: The MC system was designed to produce a multitude of linear and nonlinear magnetic fields including linear gradients of up to 10 kHz/cm (23.5 mT/m) with MC currents of 5 A per channel. With water cooling it can be driven with a duty cycle of up to 74% and ramp times of 500 μs. MR imaging experiments encoded with the developed multi-coil hardware were largely artifact-free; residual imperfections were predictable, and correctable.
Conclusion: The presented compact multi-coil array is capable of generating image encoding fields with amplitudes and quality comparable to clinical systems at very high duty cycles, while additionally enabling high-order B shimming capabilities and the potential for nonlinear encoding fields.
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http://dx.doi.org/10.1002/mrm.29692 | DOI Listing |
NMR Biomed
October 2025
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
∆B shim optimization performed at the beginning of an MR scan is unable to correct for ∆B field inhomogeneities caused by patient motion or hardware instability during scans. Navigator-based methods have been demonstrated previously to be effective for motion and shim correction. The purpose of this work was to accelerate volumetric navigators to allow fast acquisition of the parent navigated sequence with short real-time feedback time and high spatial resolution of the ∆B field mapping.
View Article and Find Full Text PDFImaging Neurosci (Camb)
May 2025
Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.
Monitoring cortical responses to neuromodulation on preclinical models can elucidate fundamental mechanisms of brain function. Concurrent brain stimulation and imaging is challenging, usually compromising spatiotemporal resolution, accuracy, and versatility. Here, we report on a non-invasive brain stimulation system with electronic control of neuromodulation parameters in a 9.
View Article and Find Full Text PDFJ Magn Reson
September 2025
Department of Biomedical Engineering, Texas A&M University, 101 Bizzell St., College Station, TX 77843, USA; Department of Electrical and Computer Engineering, Texas A&M University, 301 Wisenbaker Engineering Building, College Station, TX 77843, USA. Electronic address:
The wealth of information available from multinuclear magnetic resonance imaging and spectroscopy is largely untapped in the clinical setting. This is due to a multitude of challenges in the pipeline ranging from acquisition strategies, hardware design, processing, and interpretation/analysis. As a small part of addressing these challenges, this work presents a straightforward approach for broadband decoupling between coils.
View Article and Find Full Text PDFIEEE J Solid-State Circuits
November 2024
Department of Electrical and Computer Engineering, Rice University, Houston TX, 77005, USA.
Miniature bioelectronic implants promise revolutionary therapies for cardiovascular and neurological disorders. Wireless power transfer (WPT) is a significant method for miniaturization, eliminating the need for bulky batteries in today's devices. Despite successful demonstrations of millimetric battery-free implants in animal models, the robustness and efficiency of WPT are known to degrade significantly under misalignment incurred by body movements, respiration, heart beating, and limited control of implant orientation during surgery.
View Article and Find Full Text PDFNeuroimage
October 2024
Department of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, USA; Department of Biomedical Engineering, Yale University School of Medicine, New Haven, CT, USA.
Magnetic Resonance Spectroscopic Imaging (MRSI) is a powerful technique that can map the metabolic profile in the brain non-invasively. Extracranial lipid contamination and insufficient B homogeneity however hampers robustness, and as a result has hindered widespread use of MRSI in clinical and research settings. Over the last six years we have developed highly effective extracranial lipid suppression methods with a second order gradient insert (ECLIPSE) utilizing inner volume selection (IVS) and outer volume suppression (OVS) methods.
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