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The anti-solvent precipitation method has been investigated to produce biopolymeric nanoparticles in recent years. Biopolymeric nanoparticles have better water solubility and stability when compared with unmodified biopolymers. This review article focuses on the analysis of the state of the art available in the last ten years about the production mechanism and biopolymer type, as well as the used of these nanomaterials to encapsulate biological compounds, and the potential applications of biopolymeric nanoparticles in food sector. The revised literature revealed the importance to understand the anti-solvent precipitation mechanism since biopolymer and solvent types, as well as anti-solvent and surfactants used, can alter the biopolymeric nanoparticles properties. In general, these nanoparticles have been produced using polysaccharides and proteins as biopolymers, especially starch, chitosan and zein. Finally, it was identified that those biopolymers produced by anti-solvent precipitation were used to stabilize essential oils, plant extracts, pigments, and nutraceutical compounds, promoting their application in functional foods.
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http://dx.doi.org/10.1016/j.foodres.2023.112728 | DOI Listing |
J Sci Food Agric
August 2025
College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.
Background: Cinnamaldehyde (CA) is the main functional component of cinnamon essential oil, exhibits strong anti-microbial activity and safety. Shellac (SHL) nanoparticles enable the encapsulation and controlled release of CA while improving the physiochemical properties of chitosan (CS) films. To strengthen the anti-bacterial activity of SHL-CS films, CA-SHL nanoparticles were prepared by an anti-solvent precipitation method with Tween 80 as surfactant, and subsequently incorporated into CS film-forming solution.
View Article and Find Full Text PDFFood Chem
August 2025
Key Laboratory of Food Nutrition and Health in Universities of Shandong, College of Food Science and Engineering, Shandong Agricultural University, 61 Daizong Street, Tai'an 271018, Shandong, China. Electronic address:
In this study, unmodified/modified kudzu starch-based complexes were prepared using anti-solvent precipitation method, and gel beads were developed through cross-linking between sodium alginate and calcium ions, with kudzu starch as carrier material and Span 80 as surfactant. Subsequently, the structure characteristics, rheological properties, morphology, and controlled release of the complex were systematically investigated. Additionally, the structural features, mechanical properties, swelling stability, and controlled release behavior of gel beads were evaluated.
View Article and Find Full Text PDFPharmaceutics
June 2025
Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, Depok 16424, West Java, Indonesia.
: Solvent-intensive methods are traditionally required to extract curcumin, a potent bioactive compound from , raising environmental and safety concerns. : This study introduces an efficient and scalable extraction approach using microwave-ultrasound-assisted extraction (MUAE) combined with a natural deep eutectic solvent (NADES) composed of choline chloride and lactic acid. Process parameters, including solvent water content (20-30% /) and solid loading (4-8% /), were optimized using response surface methodology (RSM) to enhance curcumin yield.
View Article and Find Full Text PDFInt J Biol Macromol
August 2025
College of Food Science, Northeast Agricultural University, Harbin 150030, China. Electronic address:
Phytosterols, a class of phytochemicals exhibiting limited aqueous solubility and low oil solubility, possess diverse physiological functions that have attracted considerable research interest. However, their poor aqueous solubility significantly restricts practical applications in functional food systems. To address these limitations, we developed a novel core-shell nanoparticle system.
View Article and Find Full Text PDFChem Asian J
June 2025
School of Chemistry and Life Resources, Renmin University of China, Beijing, 100872, China.
The precipitation of metals from leachates is a crucial step in the hydrometallurgical recycling of solid-state electrolytes (SSEs) from waste all-solid-state lithium-ion batteries (ASSLIBs). Conventional methods, such as high-temperature distillation, low-temperature crystallization, and electro-deposition are often energy-intensive and costly. Therefore, there is a strong demand for lower-energy, cost-effective strategies to precipitate valuable metals from spent batteries.
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