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Article Abstract

Bismuth oxide nanoparticles with appropriate surface chemistry exhibit many interesting properties that can be utilized in a variety of applications. This paper describes a new route to the surface modification of bismuth oxide nanoparticles (BiO NPs) using functionalized beta-Cyclodextrin (β-CD) as a biocompatible system. The synthesis of BiO NP was done using PVA (poly vinyl alcohol) as the reductant and the Steglich esterification procedure for the functionalization of β-CD with biotin. Ultimately, the BiO NPs are modified using this functionalized β-CD system. The particle size of the synthesized BiO NPs is found to be in the range of 12-16 nm. The modified biocompatible systems were characterized using different characterization techniques such as Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray powder diffraction (XRD) and Differential Scanning Calorimetric analysis (DSC). Additionally, the antibacterial and anticancerous effects of the surface-modified BiO NP system were also investigated.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142954PMC
http://dx.doi.org/10.3390/molecules28083604DOI Listing

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