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Objective: Currently there is no parent administered scale for facial nerve function in children. We set out to assess the agreement between a newly developed parent-administered modified version of the House-Brackmann (HB) scale and the standard clinician-administered HB scale in children with Bell's palsy.
Study Design: Secondary analysis of a triple-blind, randomized, placebo-controlled trial of corticosteroids to treat idiopathic facial paralysis (Bell's palsy) in children (6 months to <18 years).
Setting: Multicenter study at pediatric hospitals with recruitment in emergency departments.
Methods: Children were recruited within 72 hours of symptom onset and assessed using the clinician-administered and the parent-administered modified HB scales at baseline, and at 1, 3, and 6 months until recovered. Agreement between the 2 scales was assessed using intraclass coefficient (ICC) and a Bland-Altman plot.
Results: Data were available for 174 of the 187 children randomized from at least 1 study time point. The mean ICC between clinician and parent HB scores across all time points was 0.88 (95% confidence interval, CI: 0.86, 0.90). The ICC for the data collected at baseline was 0.53 (95% CI: 0.43, 0.64), at 1 month was 0.88 (95% CI: 0.84, 0.91), at 3 months was 0.80 (95% CI: 0.71, 0.87) and at 6 months was 0.73 (95% CI: 0.47, 0.89). A Bland-Altman plot indicated a mean difference between the 2 scores (clinician-reported minus parent-reported) of only -0.07 (95% limits of agreement -1.37 to 1.23).
Conclusion: There was good agreement between the modified parent-administered and the clinician-administered HB scales.
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http://dx.doi.org/10.1002/oto2.44 | DOI Listing |
Eur Arch Otorhinolaryngol
September 2025
Department of Otorhinolaryngology, University of Health Sciences, Prof. Dr. Cemil Taşcıoğlu City Hospital, Istanbul, Turkey.
Purpose: To evaluate the prognostic significance of inflammatory markers, computed tomography (CT)-based facial nerve measurements, and clinical parameters in pediatric patients with Bell's palsy.
Methods: In this retrospective study, 136 patients aged 4-18 years diagnosed with Bell's palsy were evaluated. Clinical data included age, sex, affected side, initial House-Brackmann (HB) grade, recovery grades at one month and final follow-up, presence of pain, and treatment timing.
Hum Reprod
September 2025
Department of Sociology, University of Wisconsin, Madison, WI, USA.
Study Question: Are the assumptions required by the current duration (CD) approach to estimating population infertility met, and does the CD approach produce similar infertility estimates to those from the 'gold standard' incident prospective cohort approach within the same sample using fertility app data?
Summary Answer: While we find evidence of CD assumption violation, once addressed, the CD approach produces comparable infertility prevalence estimates and patterns to those from an incident prospective cohort design when selecting from the same sample of women.
What Is Known Already: The CD approach to documenting population and subgroup infertility is a promising, more feasible, and cost-effective alternative method to the incident prospective cohort design. However, as a field, we do not have sufficient evidence to use the CD approach for the study of population infertility because method assumptions have not been rigorously tested using population-based samples.
J Pediatr Surg
August 2025
Department of General Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University. Electronic address:
Backgroud: Neonatal necrotizing enterocolitis (NEC) is a severe intestinal disease potentially linked to gut microbiota dysbiosis. This prospective observational study aimed to evaluate the role of dysbiosis in NEC development.
Method: We included preterm infants with a birth weight <1500 g or gestational age <32 weeks, admitted to Shanghai Children's Hospital from April 9, 2019, to March 30, 2023.
Otolaryngol Pol
August 2025
Clinic of Social and Family Medicine, School of Medicine, University of Crete, Voutes, Greece.
<b>Introduction:</b> The COVID-19 pandemic significantly altered healthcare-seeking trends, leading to reduced emergency department (ED) visits and changes in referral patterns. By temporally distancing from the pandemic, healthcare utilization trends might be re-explored.<b>Aim:</b> This study aims to analyze the epidemiologic trends of ear, nose, and throat (ENT) cases at the ED of a tertiary hospital in Crete, Greece, after the COVID-19 pandemic.
View Article and Find Full Text PDFJ Adolesc Health
August 2025
Global Adolescent Health, Women's, Children's and Adolescents' Health Program, Burnet Institute, Melbourne, Victoria, Australia; Melbourne School of Population and Global Health, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Carlton, Victoria, Australia.
Purpose: Historically, adolescent pregnancy has been conceptualized as an outcome of child marriage, but in Southeast Asia, the contexts and drivers of adolescent pregnancy are less well-understood. This study examines the relationship between adolescent pregnancy and child marriage and explores the drivers of pregnancy in Cambodia, Indonesia, Lao People's Democratic Republic and Malaysia among adolescents who have experienced pregnancy.
Methods: Using participatory timeline interviews, we conducted semistructured interviews with 260 adolescent girls aged 15-21 years with lived experience of pregnancy in urban and rural settings in Cambodia, Indonesia, Lao People's Democratic Republic and Malaysia.