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Article Abstract
Background: The therapeutic potential of found in northern region of Balochistan, so far has been neglected.
Purpose: The current study was aimed to assess the phytochemicals and pharmacological potential of fractions isolated from .
Research Design: During phytochemicals analysis of using GC/MS showed various bioactive compounds like alkaloids, flavonoids, terpenoids, tannins, saponins, and carboxylic acids. In vitro antioxidant activity of was determined by 2, 2'- diphenyl-1-picrylhydrazyl (DPPH) Disc diffusion method was used to evaluate the antimicrobial activity.
Results: The quantitative analysis of ethyl acetate showed highest total flavonoid contents (1.19 ± .05) while ethanol with lowest value (.52 ± .01). The total phenolic contents in ethyle acetate was 1.50 ± .42, whereas ethanol showed lowest value (.77 ± .02). Ethanol exhibited excellent (88.68 ± 3.0) free radical scavenging potential measured by 1,1-diphenyl-2-picryl-hydrazyl radical scavenging assay. For antimicrobial activity, different bacterial and fungal strains like , and were selected The essential oil showed maximum % inhibition diameter (9 mm) against and (5 mm) against respectively The ethyl acetate presented % inhibition diameter (9 mm) against and (6 mm) against Anti-urease activity also showed positive response.
Conclusions: The presence of high (%) bioactive compounds with great therapeutic potential suggest that can be used as natural alternative of synthetic drugs without side effects.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026114 | PMC |
| http://dx.doi.org/10.1177/15593258231163389 | DOI Listing |
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