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http://dx.doi.org/10.17161/kjm.vol16.18707 | DOI Listing |
Altern Lab Anim
August 2025
Department of Surgery, Dr Ruth KM Pfau Civil Hospital, Karachi, Pakistan.
Recent advances in neural differentiation have unveiled new possibilities that could potentially be applied to the development of human-relevant non-animal models, for use in fields such as biomedical research and drug screening. Thus, the directed differentiation of tissue stem cells toward neural progenitor cells or neural stem cells, by small molecules and growth factors without the need for genetic manipulation, has attracted great attention. The generation of neural progenitor cells, and their proliferation and lineage commitment are regulated by signaling pathways activated by small molecules and growth factor families, including various fibroblast growth factors (FGFs).
View Article and Find Full Text PDFBMJ
August 2025
Institute of General Practice, Centre for Health and Society, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Assisted Outpatient Treatment (AOT) is a civil commitment program incorporating intensive case management and other services to support adults with a serious mental illness (SMI) and treatment adherence and ongoing engagement needs. The overarching goal of AOT programs is to minimize participants' use of emergency psychiatric care, increase their consistent use of community-based care, and reduce their potential for involvement with the legal system resulting from untreated mental health concerns. However, effectively coordinating multiple systems of care to best meet AOT clients' needs can be challenging.
View Article and Find Full Text PDFDisaster Med Public Health Prep
August 2025
Nursing Department, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Objectives: This qualitative study aimed to explore the lived experiences, challenges, and perceptions of nurses regarding disaster preparedness in non-first-tier (inland) cities in China. Building upon our previous quantitative findings, we sought to understand the psychological, professional, and organizational factors that influence nurses' disaster response capabilities in resource-limited settings.
Methods: A descriptive phenomenological approach was employed.
J Am Psychiatr Nurses Assoc
August 2025
Raymond W. Novaco, PhD, Professor, University of California, Irvine, CA, USA.
Background: Violent behavior by patients on psychiatric units is a topic that has received considerable attention, particularly with regard to its consequences for nursing staff. While studies have sought to identify predictors of violence by inpatients, there is a dearth of research on dynamic risk factors, particularly anger.
Aims: The present study investigates the viability of assessing anger among patients on an acute civil commitment psychiatric hospital unit and to examine its association with aggressive behavior.