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At the beginning of 2021, the scientific community realized the burden of COVID-19-related persistent olfactory disorders (ODs). The percentage of those infected with COVID-19 who developed severe and persistent ODs [1-3] with devastating effects on their quality of life was 5 to 40% [4,5].
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http://dx.doi.org/10.3390/pathogens12010072 | DOI Listing |
Cureus
August 2025
Cardiovascular Surgery, Hokkaido Prefectural Kitami Hospital, Kitami, JPN.
We report a case of totally endoscopic mitral valve repair for severe mitral regurgitation (MR) due to Barlow's disease in a 55-year-old man with severe pulmonary dysfunction following coronavirus disease 2019 (COVID-19) pneumonia. He had developed severe COVID-19 one month earlier, requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO). Although successfully weaned from ECMO, the patient continued to experience persistent fever and was referred to our department for suspected acute MR.
View Article and Find Full Text PDFCureus
July 2025
Pediatric Surgery, General Medicine, TMG Asaka Medical Center, Saitama, JPN.
Anterior cutaneous nerve entrapment syndrome (ACNES) is an underrecognized cause of chronic abdominal wall pain. While nerve block injections are typically used as conservative treatment, persistent or recurrent cases may require surgical neurectomy. This case series presents five patients, including a long COVID-19 case, who underwent surgical treatment for ACNES at our institution.
View Article and Find Full Text PDFCureus
July 2025
Division of Pediatrics, Yokkaichi Municipal Hospital, Yokkaichi, JPN.
Objectives: The COVID-19 pandemic introduced significant lifestyle changes, such as reduced outdoor activities, social distancing, and other public health measures. These changes may have affected maternal health and neonatal biochemical parameters linked to bone metabolism. This retrospective study aimed to evaluate the impact of pandemic-related behavioral restrictions on neonatal biochemical markers, including calcium, phosphate, magnesium, intact parathyroid hormone (iPTH), and alkaline phosphatase (ALP), measured on the first day of life across three distinct time periods (pre-COVID-19, COVID-19 pandemic, and post-COVID-19).
View Article and Find Full Text PDFJMIR Public Health Surveill
August 2025
see Authors' Contributions section, .
Background: The COVID-19 pandemic exposed significant limitations in existing data infrastructure, particularly the lack of systems for rapidly collecting, integrating, and analyzing data to support timely and evidence-based public health responses. These shortcomings hampered efforts to conduct comprehensive analyses and make rapid, data-driven decisions in response to emerging threats. To overcome these challenges, the US National Institutes of Health launched the Rapid Acceleration of Diagnostics (RADx) initiative.
View Article and Find Full Text PDFAnn Otol Rhinol Laryngol
August 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, China.
Objectives: Olfactory dysfunction (OD) is a common symptom of SARS-CoV-2 infection. This study aimed to determine the prevalence and clinical characteristics of OD, evaluate its recovery trajectory, and identify predictors of its onset and persistence.
Methods: We conducted a prospective cohort study of 3477 participants recruited through an online questionnaire between December 1 and 31, 2022.