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An injectable polysaccharide supramolecular hydrogel was successfully fabricated from opened D-glucopyranosyl β-cyclodextrin with four aldehyde groups (ACD) cross-linked with biomacromolecule chitosan (CS), which was not only beneficial to the clustering-triggered emission of CS with high quantum yield (32.25%), but also could co-assemble with a first stage acceptor triphenylamine derivative (TPA) and encapsulate Cyanine 5 (Cy5) or Nile blue (NiB) achieving supramolecular cascade energy transfer from the cross-linked polymer to the dyes, leading to fluorescence emission at 673 nm or 680 nm, and could be further applied in cell imaging.
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http://dx.doi.org/10.1039/d2cc06908c | DOI Listing |
Anal Chem
September 2025
State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, College of Energy, Discipline of Intelligent Instrument and Equipment, State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, Xiamen University, Xiamen 361
Rolling circle amplification (RCA) has revolutionized nucleic acid detection owing to its isothermal simplicity. However, over two decades of clinical application have been hampered by off-target amplification and incompatibility with double-stranded DNA (dsDNA). Herein, a strategy, specifically cleavage of rationally designed DNA/RNA chimeric hairpin preprimer by dsDNA-targeted CRISPR/Cas12a to rlease ssRNA for initiating RCA (SCOPE-RCA), is proposed for nucleic acid identification of African swine fever virus (ASFV).
View Article and Find Full Text PDFJ Elect Propuls
September 2025
Department of Aerospace Engineering, Universidad Carlos III de Madrid, Leganés, Spain.
The collisionless cross-field electron transport in an plasma configuration, representative of a Hall thruster, is studied using bispectral analysis on the data of a fully-kinetic simulation. The nonlinear, in-phase interaction of the oscillations of the azimuthal electric field and the electron density, both tied to the fundamental electron cyclotron drift instability (ECDI) mode, is found to be the main driver of electron transport. Higher-wavenumber ECDI modes do not drive anomalous transport directly; however, they are nonlinearly coupled with each other and with the fundamental ECDI mode.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
State Key Laboratory of Green Pesticides, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China. Electronic address:
The overreliance on traditional chemical fungicides, combined with the emergence of resistance, poses significant challenges for food safety. Early blight, caused by the fungal pathogen Alternaria solani (A. solani), is among the most significant contributors to pre- and postharvest yield losses in tomato cultivation.
View Article and Find Full Text PDFBiosens Bioelectron
September 2025
College of Life Sciences, China Jiliang University, Hangzhou, 310018, China. Electronic address:
Glucose sensors are critical analytical devices designed for precise and continuous monitoring of glucose concentrations, playing a pivotal role in healthcare, particularly in diabetes management. Here, we synthesis glucose oxidase (GOx)/Se hydrogel to detect the glucose, thereby generating measurable electrical signals. Further, the transfection of electronic signals rely on the poly(dopamine) (PDA) grid in hydrogel.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, China. Electronic address:
The global burden of diabetes has been exacerbated by a shift in dietary patterns toward diets rich in refined sugars, saturated fats and energy-dense nutrients. Diabetes is a metabolic disease characterized by chronic hyperglycemia. Persistently elevated blood glucose levels can lead to microvascular complications that contribute greatly to reduced quality of life, disability or death.
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