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Durable implantable left ventricular assist devices (LVADs) have been shown to improve survival and quality of life for patients with stage D heart failure. Even though LVADs remain underused overall, the number of patients with heart failure supported with LVADs is steadily increasing. Therefore, general cardiologists will increasingly encounter these patients. In this review, we provide an overview of the field of durable LVADs. We discuss which patients should be referred for consideration of advanced heart failure therapies. We summarize the basic principles of LVAD care, including medical and surgical considerations. We also discuss the common complications associated with LVAD therapy, including bleeding, infections, thrombotic issues, and neurologic events. Our goal is to provide a primer for the general cardiologist in the recognition of patients who could benefit from LVADs and in the principles of managing patients with LVAD. Our hope is to "demystify" LVADs for the general cardiologist.
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http://dx.doi.org/10.1161/JAHA.122.027251 | DOI Listing |
Rev Cardiovasc Med
August 2025
Department of Cardiovascular Medicine, University Hospital Leuven, 3000 Leuven, Belgium.
Intravascular optical coherence tomography (OCT) has represented a revolutionary invasive imaging method, offering high-resolution cross-sectional views of human coronary arteries, thereby promoting a significant evolution in the understanding of vascular biology in both acute and chronic coronary pathologies. Since the development of OCT in the early 1990s, this technique has provided detailed insights into vascular biology, enabling a more thorough assessment of coronary artery disease (CAD) and the impact of percutaneous coronary intervention (PCI). Moreover, a series of recent clinical trials has consistently demonstrated the clinical benefits of intravascular imaging (IVI) and OCT-guided PCI, showing improved outcomes compared to angiography-guided procedures, particularly in cases of complex coronary pathology.
View Article and Find Full Text PDFArch Cardiovasc Dis
September 2025
CIC INSERM 1410, 97410 Saint-Pierre, France; Department of Cardiology, La Réunion University Hospital, 97400 Saint-Denis, France. Electronic address:
Background: Artificial intelligence has emerged as a promising tool to optimize patient care in the field of cardiovascular medicine. However, data on its adoption and utilization by healthcare professionals are scarce.
Aim: To explore the factors that support or hinder the adoption of artificial intelligence in cardiology in France.
JACC Asia
September 2025
Department of Cardiology, National Heart Center Singapore, Singapore, Singapore; Duke-National University of Singapore Medical School, Singapore, Singapore. Electronic address:
Background: Preventing frailty is crucial for improving outcomes in aging populations at heightened cardiovascular risk, yet implementation in real-world practice remains challenging. The authors previously reported low use of frailty strategies among cardiologists in Asia.
Objectives: The aim of this study was to explore the barriers to frailty implementation among cardiologists, other physicians, and nurses.
Eur Heart J Case Rep
September 2025
Cardio-Thoracic-Vascular Department, Cardiology Unit, Azienda Ospedaliera Carlo Poma, ASST Mantova, Str. Lago Paiolo 10, Mantova 46100, Italy.
Background: While advances in technology and procedural techniques have significantly improved outcomes post-PCI, two pharmacological strategies have gained particular attention for their effectiveness in reducing long-term cardiovascular (CV) risk: anti-platelet therapies and lipid-lowering therapies (LLT). The 10-year recurrence risk for major CV events remains as high as 10-30%, due to various pathophysiological pathways collectively known as residual risk (RR), even with optimal CV risk factor management after acute coronary syndrome (ACS). RR includes factors such as elevated lipoprotein(a) [Lp(a)], triglycerides, pro-thrombotic states, hyperglycemia, and persistent subclinical arterial inflammation.
View Article and Find Full Text PDFJ Am Heart Assoc
September 2025
Department of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition Fudan University Shanghai China.
Background: Loss of a stable spousal relationship has been associated with a high risk of morbidity and premature death, yet there is limited evidence on the association between marital failure and the risk of subsequent heart failure (HF). We examined the association between marital failure and the risk of subsequent HF in large prospective studies.
Methods: This cohort study utilized data from Kailuan Study I and Kailuan Study II.