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http://dx.doi.org/10.1097/MPG.0000000000003663 | DOI Listing |
Zhong Nan Da Xue Xue Bao Yi Xue Ban
May 2025
Department of Outpatient, Third Xiangya Hospital, Central South University, Changsha 410013.
Objectives: Urinary calculi are characterized by a high recurrence rate, and patients' adherence to self-management after discharge directly affects health outcomes. Traditional offline follow-up models often face problems such as poor compliance and uneven allocation of medical resources, making it difficult to meet individualized health management needs. Remote follow-up provides a novel solution to optimize long-term management, improve health literacy, and enhance clinical outcomes.
View Article and Find Full Text PDFEur J Pharm Sci
September 2025
Department of Medicinal Chemistry, Uppsala University, SE-75123 Uppsala, Sweden. Electronic address:
Subcutaneous (SC) injection is the primary alternative to oral administration for therapeutic proteins and peptides. However, bioavailability and absorption rate are often variable and difficult to predict. Therefore, there is a need for new biorelevant and predictive SC in vitro methods.
View Article and Find Full Text PDFDrugs
September 2025
Division of Geriatric Psychiatry, Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine, 1438 S. Grand Boulevard, St. Louis, MO, 63104, USA.
This narrative review explores current pharmacological treatments for agitation in Alzheimer's disease (AD). Agitation, a common and difficult-to-manage symptom in AD, often requires targeted intervention. While nonpharmacological methods, such as behavioral therapy and environmental modifications, are considered first line, they may not always be effective.
View Article and Find Full Text PDFJ Invest Dermatol
September 2025
Unit for Paediatric & Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, UK.
Many new biologic treatments and small molecule agents are emerging and being approved for treating atopic dermatitis (AD). Robust evidence, based on large sample sizes from real-world clinical settings, are needed to investigate the use of these new therapies, However, adequate sample sizes of patient data are difficult to obtain within one country alone, requiring international collaboration and data aggregation. To address this need for cooperative research, we investigated the feasibility for an international collaboration of registries to gather data from real-world clinical settings on patients' use of new systemic treatments for AD by creating a federated network between national registries that enables an analysis environment protecting privacy of information and ensuring compliance with General Data Protection Regulation.
View Article and Find Full Text PDFClin Oncol (R Coll Radiol)
July 2025
Department of Clinical Oncology, The Christie NHS Foundation Trust, Wilmslow Rd, Manchester M20 4BX, United Kingdom.
Aims: Single-handed oncology practice occurs when only one clinician covers a particular tumour site in a department. There is no quantified evidence about experiences of single-handed practice or its impact in oncology. A team supported by the Tessa Jowell Brain Cancer Mission interviewed 35 neuro-oncologists in the United Kingdom (UK) to better understand the workload, challenges and support networks of single-handed neuro-oncologists compared with those of neuro-oncologists at larger centres.
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