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Background: Hemodialysis (HD) and peritoneal dialysis (PD) are deemed medically equivalent for therapy of end-stage renal disease (ESRD) and reimbursed by the German statutory health insurance (SHI). However, although the home dialysis modality PD is associated with higher patient autonomy than HD, for unknown reasons, PD uptake is low in Germany. Hence, we compared HD with PD regarding health economic outcomes, particularly costs, as potentially relevant factors for the predominance of HD.
Methods: Claims data from two German health insurance funds were analysed in a retrospective cohort study regarding the prevalence of HD and PD in 2013-2016. Propensity score matching created comparable HD and PD groups ( = 436 each). Direct annual health care costs were compared. A sensitivity analysis included a comparison of different matching techniques and consideration of transportation costs. Additionally, hospitalisation and survival were investigated using Poisson regression and Kaplan-Meier curves.
Results: Total direct annual average costs were higher for HD (€47,501) than for PD (€46,235), but not significantly ( = 0.557). The additional consideration of transportation costs revealed an annual cost advantage of €7000 for PD. HD and PD differed non-significantly in terms of hospitalisation and survival rates ( = 0.610/ = 0.207).
Conclusions: PD has a slight non-significant cost advantage over HD, especially when considering transportation costs.
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http://dx.doi.org/10.3390/ijerph192114007 | DOI Listing |
PLoS One
September 2025
College of Intelligent Science and Control Engineering, Jinling Institute of Technology, Nanjing, China.
Traffic congestion frequently occurs in the drop-off zones of large integrated passenger hubs, posing significant challenges to the efficient utilization of lane space. This study develops a First-In-First-Out (FIFO) taxi drop-off decision-making model, incorporating both static and dynamic Logit frameworks grounded in panel data analysis. The model accounts for heterogeneity across vehicles, temporal variations, and spatial factors influencing drop-off decisions.
View Article and Find Full Text PDFACS Omega
September 2025
Dept. of Electrical and Electronic Engineering, Noakhali Science and Technology University, Noakhali 3814, Bangladesh.
Perovskite solar cells (PSCs) are rapidly advancing due to their high power conversion efficiencies (PCEs) and low fabrication costs. However, their commercialization is hindered by lead toxicity and the use of expensive materials, such as Spiro-OMeTAD and gold electrodes. This study presents a comprehensive SCAPS-1D simulation-based analysis of 14 perovskite absorber materials, spanning both Pb-based and lead-free compounds, under a unified device architecture using low-cost, nontoxic components: ZnO as the electron transport material (ETM), PEDOT:PSS + WO as a dual hole transport material, and nickel as the back contact.
View Article and Find Full Text PDFTelemed Rep
July 2025
Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Introduction: Cardiovascular disease is a leading global cause of death, with coronary artery disease often requiring coronary artery bypass grafting (CABG). Inadequate rehabilitation increases health risks and costs, and low adherence to center-based rehabilitation has prompted interest in telerehabilitation. Despite technological advances, the global implementation of telerehabilitation for CABG patients remains underexplored.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
August 2025
Animal Genetics, University of Tuebingen, 72076 Tuebingen, Germany.
Background: Membrane transport proteins are critical determinants of systemic and intracellular drug levels, thereby contributing substantially to drug response and/or adverse drug reactions. Therefore, the U.S.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Department of Material Science & Engineering, City University of Hong Kong, Kowloon, 999077, Hong Kong P.R. China.
Organic solar cells (OSCs) with p-i-n architecture usually exhibit decent efficiency due to the easily tunable energy levels of organic interfacial layers (ILs). However, their operational lifetime is limited by the morphological instability of organic ILs especially the electron-transporting layer (ETL) that shows strong self-aggregation tendency. Besides, organic ETLs are confronted with significant challenges including large batch-to-batch variations and high costs.
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