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Deep infiltrating pelvic endometriosis and its surgical management is associated with a risk of major postoperative complications. Magnetic Resonance Imaging (MRI) is recommended preoperatively in order to obtain the most precise mapping of the extent of endometriotic lesions. The aim of this work was to assess the feasibility and clinical interest of 3D modeling by surface rendering as a preoperative planning tool in a patient with deep infiltrating pelvic endometriosis. We report on a 42 years old patient with history of endometriosis and persistent pain underwent pre operative imaging with MRI that was consistent with deep infiltrating endometriosis. A 3D model of the deep infiltrating endometriosis was generated from the MRI and retrospectively compared to the intra-operative findings. The nodule's location and relationship to the uterus and the rectum was clearly defined by the 3D model and correlated with surgical findings. Virtual reality based on 3D models could be an interesting tool to assist in the preoperative planning of complex surgeries.
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http://dx.doi.org/10.1016/j.jogoh.2022.102500 | DOI Listing |
Zhonghua Bing Li Xue Za Zhi
September 2025
Department of Pathology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou 450003, China.
To investigate the clinicopathological features, genetic characteristics, and differential diagnosis of glomangiomatosis with uncertain malignant potential. Two cases of glomangiomatosis with uncertain malignant potential were collected at Henan Provincial People's Hospital from 2013 and 2023. Immunohistochemistry and next generation sequencing (DNA-seq) were used to detect the related protein and gene variation.
View Article and Find Full Text PDFCancer Immunol Res
September 2025
University of Pennsylvania, Philadelphia, PA, United States.
Pancreatic ductal adenocarcinoma (PDA) is defined by a myeloid-enriched microenvironment and has shown remarkable resistance to immune checkpoint blockade (e.g., PD-1 and CTLA-4).
View Article and Find Full Text PDFAnn Med
December 2025
Department of Gynecology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Objective: To evaluate preoperative serum calcium levels and their association with deep infiltrating endometriosis (DIE) in ovarian endometrioma.
Design: A retrospective, observational cohort study.
Participants: A total of 2,557 women who underwent surgery for benign ovarian tumors were initially enrolled.
J Dent
September 2025
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610041, China; Department of Operative Dentistry and Endodontics, West China School of Stomatology, Sichuan University, Chengdu 610041, China. E
Objectives: The aim of this study is to explore the specific application scenarios of quantitative light-induced fluorescence (QLF) in the detection and treatment of early caries, so as to provide more evidence for the clinical application of QLF.
Methods: (1) The accuracy of QLF in detecting the lesion depth of early caries was evaluated by combining transverse microradiography (TMR) and spectrophotometer analysis (n=6). (2) Resin infiltration therapy was used as a representative method for the treatment of early caries to evaluate the ability of QLF in assessing the therapeutic effect on early caries (n=6).
Sci Adv
September 2025
Key Laboratory of Ocean Observation and Forecasting, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266400, China.
A large hydrothermal field at depths >4300 meters was found on the east Caroline plate in the western Pacific Ocean. Here, we show that large hydrothermal pipes with steep walls and breccia-dominated bottoms suggest explosions of billion metric tons of TNT (trinitrotoluene) equivalent. More than 800 short-duration seismic events were detected within 28 days along a 150-kilometer profile, indicating widespread ongoing explosive gas release.
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