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Tuberculosis is an endemic disease in India for decades, and its coexistence in the patients with malignancy cannot be ignored. The non-specific uptake of 2-deoxy-2-[fluorine-18] fluoro-D-glucose in active infection and malignancy can affect the diagnosis and management of patients. However, characteristic anatomical features of the lesion aid not only in its localization but also in diagnosis. We share an interesting case of necrotizing granulomatous inflammation of dorsal spine mimicking skeletal metastases in a treated case of carcinoma cervix.
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http://dx.doi.org/10.1186/s41824-022-00151-4 | DOI Listing |
Pediatr Nephrol
September 2025
Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Background: Kidney involvement in pediatric sarcoidosis is rare and often underrecognized, leading to diagnostic delays and treatment challenges. We report six patients with renal sarcoidosis to highlight their diverse presentations and outcomes and challenges in management.
Methods: Medical records of patients diagnosed with renal sarcoidosis during 2020-24 were reviewed.
Cureus
August 2025
Norton College of Medicine, SUNY Upstate Medical University, Syracuse, USA.
Hydralazine is an antihypertensive that can induce immune-related adverse effects, such as hydralazine-induced lupus and hydralazine-induced antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV). AAV involves necrotizing inflammation of small blood vessels, manifesting as fever, malaise, arthralgia, and myalgia, potentially leading to organ failure. Diagnosis includes clinical evaluation, serological testing for ANCA, and histopathological examination, confirmed by necrotizing granulomatous inflammation in affected tissues.
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September 2025
Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Purpose: To report a rare case of bilateral necrotising retinitis caused by a potentially novel human adenovirus D (HAdV-D) in a post-bone marrow transplant patient and to highlight the diagnostic challenges and therapeutic role of intravenous cidofovir, alongside a review of previously reported cases of human adenovirus (HAdV) retinitis.
Methods: Retrospective case report.
Results: A 60-year-old man with a history of acute myeloid leukaemia, in remission post-bone marrow transplant, presented with bilateral hypertensive granulomatous panuveitis and necrotising retinitis.
Avian Pathol
September 2025
North of England Zoological Society (Chester Zoo), Chester, UK.
Avian pseudotuberculosis infection usually presents as well-demarcated visceral necrotic foci, typically affecting the gastrointestinal tract, liver and spleen. This case series describes an atypical presentation of (Yptb) characterized by severe chronic myositis, arthritis and osteomyelitis in five village weavers (), and acute osteomyelitis and myositis associated with septicaemia in an oriental magpie robin () from a zoological collection. Clinical signs of the weavers included lethargy, poor flying ability and focally extensive periarticular and muscular swelling, whereas the magpie robin was found dead without premonitory signs.
View Article and Find Full Text PDFExp Parasitol
September 2025
Department of Medical Parasitology, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt. Electronic address:
Background: Allovahlkampfia spelaea (A. spelaea) is a free-living amoeba that has recently been recognized to cause Acanthamoeba-like keratitis, the treatment of which is complex. The pathogenic potential of Allovahlkampfia spp.
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