Publications by authors named "Emma A Davies"
Adenoviral Retinitis: A Rare Case Presentation of a Common Virus.
Ocul Immunol Inflamm
September 2025
Purpose: To report a rare case of bilateral necrotising retinitis caused by a potentially novel human adenovirus D (HAdV-D) in a post-bone marrow transplant patient and to highlight the diagnostic challenges and therapeutic role of intravenous cidofovir, alongside a review of previously reported cases of human adenovirus (HAdV) retinitis.
Methods: Retrospective case report.
Results: A 60-year-old man with a history of acute myeloid leukaemia, in remission post-bone marrow transplant, presented with bilateral hypertensive granulomatous panuveitis and necrotising retinitis.
Article Synopsis
- * A custom SureSelect target enrichment assay was modified to improve its effectiveness in sequencing adenoviruses from clinical samples, leading to successful whole genome sequencing of 91.6% of samples.
- * While the modified protocol shows good performance, particularly with respiratory and fecal samples, further investigation is needed due to some variations in enrichment success based on sample type and adenovirus concentration.
Paediatric acute hepatitis of unknown aetiology: a national investigation and adenoviraemia case-control study in the UK.
Lancet Child Adolesc Health
November 2023
Background: An increase in acute severe hepatitis of unknown aetiology in previously healthy children in the UK in March, 2022, triggered global case-finding. We aimed to describe UK epidemiological investigations of cases and their possible causes.
Methods: We actively surveilled unexplained paediatric acute hepatitis (transaminase >500 international units per litre) in children younger than 16 years presenting since Jan 1, 2022, through notifications from paediatricians, microbiologists, and paediatric liver units; we collected demographic, clinical, and exposure information.
Article Synopsis
- Monkeypox (MPXV) is a less severe, emerging zoonotic viral disease that poses a global health threat, primarily transmitted through close contact and affecting high-risk groups like healthcare workers and men who have sex with men.* -
- The disease is characterized by skin lesions, primarily on the face and extremities, and while most cases are mild, it can have long-term health effects.* -
- Vaccination against MPXV is available but should target high-risk individuals, and a coordinated "one globe, one health" approach is crucial to manage the outbreak and leverage lessons from past pandemics like COVID-19.*
Introduction: An outbreak of Influenza B occurred at a large United Kingdom (UK) regional adult cystic fibrosis (CF) centre in May 2016. This was late in the UK 2015-2016 influenza season and occurred on a specialist ward with strict infection control procedures. This study investigates the spread of influenza, clinical consequences and potential contributing factors.
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