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http://dx.doi.org/10.1053/j.gastro.2022.10.005 | DOI Listing |
Open Access Rheumatol
August 2025
Department of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, 510632, People's Republic of China.
Objective: To evaluate the efficacy of baricitinib in combination therapy for managing refractory, rapidly progressive systemic sclerosis (SSc) with severe cardiac conduction defects and interstitial lung disease (ILD).
Methods: A 48-year-old male patient with SSc complicated by significant cardiac enlargement, third-degree atrioventricular block, heart failure, progressive ILD, and partial intestinal obstruction was included in the study. Prior treatments with mycophenolate mofetil (MMF), tacrolimus, and cyclophosphamide (CTX) had shown limited efficacy.
Front Microbiol
August 2025
Department of Allergy, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Introduction: Hepatic sinusoidal obstruction syndrome (HSOS) is a vascular liver disease with a high mortality rate, and treatment methods are limited. Rivaroxaban is an oral anticoagulant. This study aimed to investigate the pharmacological effect and potential mechanism of rivaroxaban on HSOS.
View Article and Find Full Text PDFInfect Disord Drug Targets
September 2025
Department of Chemistry, NFC Institute of Technology, Multan, Pakistan.
Introduction: Targeted infection imaging is crucial for accurate diagnosis in postpartum women. This project uses 99mTc-labeled cefixime to develop a radiopharmaceutical for detecting, distinguishing, and treating infections and abscesses in women.
Method: Technetium (TcO4-) chelated with cefixime, reduced by stannous chloride, confirmed via thin-layer chromatography.
Int J Surg Case Rep
September 2025
Department of General Surgery A21, Charles Nicolle University Hospital, Faculty of Medicine of Tunis, Tunisia.
Introduction And Importance: Foreign body ingestion is a significant clinical concern, particularly among elderly and psychiatric patients, often leading to complications such as intestinal obstruction. In this article, we present an intriguing case of dual intestinal and urinary obstruction caused by the ingestion of a dental bridge in a patient with Bricker urinary diversion. Through this rare case, we aim to explore the diagnostic and therapeutic challenges associated with such incidents, supported by a comprehensive review of the literature.
View Article and Find Full Text PDFFront Surg
August 2025
Department of Imaging, Taixing People's Hospital Affiliated to Yangzhou University, Taixing, Jiangsu, China.
Objective: To analyze the clinical characteristics, etiological distribution, and treatment outcomes of Hepatic Portal Venous Gas (HPVG) in a cohort of elderly patients with multiple comorbidities, and to evaluate the impact of early surgical intervention on survival rates.
Methods: A retrospective study was conducted on 25 patients with HPVG admitted to Taixing People's Hospital of Yangzhou University from January 2010 to June 2024. The study included demographic characteristics, symptoms, comorbidities, etiology, laboratory and abdominal CT results, treatment, and outcomes.