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Carrot processing industries produce 25-30% of waste in the form of carrot rejects, peels, and pomace which contain a large amount of high-value bioactive components. Green extraction of the bioactive components from carrot rejects with green solvents using closed-vessel energy-intensive microwave-assisted extraction was the objective of this work. In this work, three experimental studies were implemented. One uses 8 different green solvents for maximum yield of bioactive using green technology, and the other for the optimization of Microwave-assisted Extraction (MAE) parameters to enhance the bioactive components yield. Response Surface Methodology was employed to optimize the processing parameters including temperature, time, solid to solvent ratio, and solvent type. The optimized extraction conditions: treatment temperature of 50 °C for 5 min gave a significantly higher yield of total carotenoids (192.81 ± 0.32 mg carotenoids/100 g DW), total phenolic (78.12 ± 0.35 g GAE/100 g DW), and antioxidants by FRAP (5889.63 ± 0.47 mM TE/100 g DW), ABTS (1143.65 ± 0.81 mM TE/100 g DW), and DPPH (823.14 ± 0.54 mM TE/100 g DW) using a solvent combination of hexane and ethanol (1:3) with solid to solvent ratio of 1:40 (w/v). This green technology in combination with GRAS solvents promoted the best recovery of bioactive from carrot rejects. Moreover, the solid residue remained after the extraction of bioactive components exhibited higher carbon content (46.5%) and calorific value (16.32 MJ/kg), showcasing its potential to be used as an energy source.
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http://dx.doi.org/10.1038/s41598-022-20971-5 | DOI Listing |
Ethnopharmacological Relevance: Heart failure (HF), the terminal stage of various cardiovascular diseases, represents a significant threat to global health. Fuxin Decoction (FXD), a classical Traditional Chinese Medicine (TCM) formula, has demonstrated therapeutic efficacy in HF treatment. However, its bioactive components and precise mechanisms remain to be elucidated.
View Article and Find Full Text PDFInt J Biol Macromol
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Institute of Agricultural Resources and Environment, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014, China; Jiangsu Collaborative Innovation Center for Solid Organic Waste Resource Utilization, Nanjing, 210095, China.
Humic acid (HA) and fulvic acid (FA) are the most abundant components of the organic matter in the compost. However, the key chemical structures for the bioactivity of HA/FA and how these structures being affected by composting conditions are not fully understood. The changes in chemical compositions between HA and FA were primarily driven by differences in the contents of carboxyl C, aromatic C, O- alkyl C and C/N ratio.
View Article and Find Full Text PDFJ Ethnopharmacol
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School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China. Electronic address:
Ethnopharmacological Relevance: Lonicera caerulea var. edulis is an Oroqen medicine with fever relief, detoxification, and anti-inflammatory activities. However, pharmacological and chemical research on its leaves is limited.
View Article and Find Full Text PDFArch Toxicol
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Laboratorio de Proteómica, Facultad de Microbiología, Instituto Clodomiro Picado, Universidad de Costa Rica, San José, 11501, Costa Rica.
The scorpion Hottentotta judaicus inhabits the Levant region of the Middle East, including Lebanon, Jordan, Palestine, and Israel. While previous research focused on its insecticidal properties and sodium-channel-targeting toxins, its venom remains largely unexplored using modern proteomic approaches. We analyzed the venom composition of H.
View Article and Find Full Text PDFJ Sci Food Agric
September 2025
College of Food Science & Technology, Shanghai Ocean University, Shanghai, China.
Background: Kaempferol (KAE), a bioactive flavonoid, has limited solubility and stability in water. Zein-gum arabic (GA) nanoparticles (NPs) are promising carriers for KAE, but the influence of preparation methods on their structure and properties remains unclear. This study investigated the effect of preparation method on the structure and properties of KAE-loaded zein-GA NPs.
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