Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Five undescribed diterpenoids, including two ent-cleistanthane-type diterpenoids aconicleistanthanes A and B, a hetisine-type diterpenoid aconihetisine A, two aconitines-type diterpenoids aconicarmines A and B, and thirteen known diterpenoids alkaloids, were co-isolated from the lateral root of the Aconitum carmichaelii Debeaux (Ranunculaceae). Their structures were elucidated based on spectroscopic methods, and the absolute configurations were determined by X-ray diffraction and electronic circular dichroism (ECD) calculations. Among them, aconicleistanthanes A and B as ent-cleistanthane-type diterpenoid featuring a unique five-membered lactone D ring, is the first reported example of ent-cleistanthane-type diterpenoids in the Aconitum, which provided a new type of diterpene metabolites for Aconitum and enriched the chemical space of the plant of the Aconitum. In the bioassays, aconicleistanthane A significantly suppressed the production of pro-inflammatory mediators (IL-6, IL-1β and COX-2) and the protein expression of the enzyme iNOS at the concentration of 6.25 μM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.phytochem.2022.113455 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The effect of different obturation techniques on post-obturation pain and sealer extrusion in single-visit root canal treatment: a prospective clinical randomized study.
Clin Oral Investig
September 2025
Department of Endodontics, Faculty of Dentistry, Galala University, Suez, Egypt.
Objectives: Postoperative pain remains a significant concern in endodontics. The main aim of this clinical trial was to assess the impact of various obturation technique and sealer types on post-obturation pain and sealer extrusion in single-visit nonsurgical root canal treatments.
Materials And Methods: Study participants were recruited through consecutive sampling from patients referred to the Endodontic Department, Faculty of Dentistry, Institution University, diagnosed as asymptomatic irreversible pulpitis.
Isolation of a Novel Plant Growth-Promoting Dyella sp. From a Danish Natural Soil.
Environ Microbiol Rep
October 2025
DynaMo Center, Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen, Frederiksberg, Denmark.
Natural soils are reservoirs of potentially beneficial microbes that can improve plant performance. Here, we isolated 75 bacterial strains from surface-sterilised roots of Arabidopsis thaliana (Arabidopsis) grown in a natural soil derived from an alder swamp. Culture-dependent isolation of individual strains from the roots, followed by monoassociation-based screening, identified seven bacteria that promoted Arabidopsis seedling weight.
View Article and Find Full Text PDFTranscriptome Analysis Reveals the Mechanism of Early Branching of Balsa (Ochroma lagopus Swartz).
Physiol Plant
September 2025
CAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Menglun, China.
Balsa (Ochroma lagopus Swartz), the world's lightest wood and a crucial material in wind turbine blades, holds significant potential to contribute to carbon neutrality efforts when cultivated in tropical areas such as Xishuangbanna, China. However, balsa trees planted in Xishuangbanna exhibit early branching, resulting in reduced wood yield. Our study investigated the pivotal factors in regulating shoot apical dominance and branching by comparing an early-branching cultivar from Indonesia with a late-branching cultivar from Ecuador.
View Article and Find Full Text PDFHormonal regulation of cell fate plasticity of xylem-pole-pericycle lineage in Arabidopsis roots.
Mol Plant
September 2025
Organismal and Evolutionary Biology Research Programme, Faculty of Biological and Environmental Sciences and Viikki Plant Science Centre, University of Helsinki, Helsinki, Finland. Electronic address:
In Arabidopsis roots, xylem-pole-pericycle (XPP) cells exhibit dual cell fates by contributing to both lateral root (LR) and cambium formation. Despite the significant progress in understanding these processes individually, the mechanism deciding between these two fates and its contribution on root architecture and secondary growth remain unknown. Here we combined lineage tracing with molecular genetics to study the regulation of fate plasticity of XPP cell lineage.
View Article and Find Full Text PDFFrom Growth to Survival: Aux/IAA Genes in Plant Development and Stress Management.
Plant Sci
September 2025
Fermentation and Phytofarming Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur-176061, Himachal Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India. Electronic address:
Auxin, one of the earliest recognized and extensively investigated phytohormones, is crucial in plant growth and survival in adverse environmental conditions. Two gene families primarily regulate auxin signaling: auxin response factors (ARFs) and auxin/indole-3-acetic acid (Aux/IAA). Aux/IAA family proteins are recognized as essential elements of the nuclear auxin signaling system, inhibiting gene transcription in their presence and facilitating gene activation upon their degradation.
View Article and Find Full Text PDF