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We present a high-throughput method for identifying and characterizing individual nanowires and for automatically designing electrode patterns with high alignment accuracy. Central to our method is an optimized machine-readable, lithographically processable, and multi-scale fiducial marker system─dubbed LithoTag─which provides nanostructure position determination at the nanometer scale. A grid of uniquely defined LithoTag markers patterned across a substrate enables image alignment and mapping in 100% of a set of >9000 scanning electron microscopy (SEM) images (>7 gigapixels). Combining this automated SEM imaging with a computer vision algorithm yields location and property data for individual nanowires. Starting with a random arrangement of individual InAs nanowires with diameters of 30 ± 5 nm on a single chip, we automatically design and fabricate >200 single-nanowire devices. For >75% of devices, the positioning accuracy of the fabricated electrodes is within 2 pixels of the original microscopy image resolution. The presented LithoTag method enables automation of nanodevice processing and is agnostic to microscopy modality and nanostructure type. Such high-throughput experimental methodology coupled with data-extensive science can help overcome the characterization bottleneck and improve the yield of nanodevice fabrication, driving the development and applications of nanostructured materials.
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http://dx.doi.org/10.1021/acsnano.2c08187 | DOI Listing |
J Hazard Mater
September 2025
College of Environment and Climate, Guangdong Provincial Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou 510632, China. Electronic address:
Antimicrobial resistance is one of the most substantial challenges for global public health. To address the inefficient elimination of intracellular resistance genes (i-ARGs) in antibiotic-resistant bacteria (ARB) by peracetic acid (PAA) oxidation, we developed an integration strategy (NW-EP/EA) of nanowire-confined electroporation (NW-EP) of ARB cells and nanowire-confined electroactivation (NW-EA) of PAA with a sequential oxidation-reduction process. The locally enhanced electric field and electrocatalytic activity over NW tips prompted the formation of electroporation pores on ARB cells and the generation of reactive ⋅OH and RO⋅ radicals by PAA electroactivation.
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Faculty of Space Technologies, AGH University of Kraków, al. A. Mickiewicza 30, 30-059 Kraków, Poland.
Anodised metal matrices represent a versatile and multifunctional platform for the development of advanced materials with tunable physicochemical properties. Through electrochemical oxidation processes-commonly referred to as anodisation-metals such as aluminium, titanium, niobium, zinc and tantalum can be transformed into structured oxide layers with defined porosity, thickness and surface morphology. These methods enable the fabrication of ordered nanoporous arrays, nanotubes and nanowires, depending on the process parameters and the type of metal.
View Article and Find Full Text PDFAnal Chem
September 2025
College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P. R. China.
Electrochemical nanosensors with high spatiotemporal resolution are important tools for single-cell analysis. However, it remains a great challenge to prepare electrochemical nanosensors with excellent and highly reproducible performance. Herein, we propose a novel strategy to assemble electrochemical nanosensors through functionalized nanowires prepared by utilizing porous anodic aluminum oxide (AAO) as the template.
View Article and Find Full Text PDFACS Nano
September 2025
Institute of Micro- and Nanostructure Research (IMN) and Center for Nanoanalysis and Electron Microscopy (CENEM), Interdisciplinary Center for Nanostructured Films (IZNF), Friedrich-Alexander-Universität Erlangen-Nürnberg, Cauerstrasse 3, 91058 Erlangen, Germany.
Silver nanowire (AgNW) networks have emerged as one of the most promising materials for flexible transparent conductive electrodes. These wires offer excellent electrical, optical, and mechanical properties and can be applied using low-cost printing techniques with the potential for upscaling. To elucidate the mechanical properties of nanowire networks for use in flexible electronics, it is essential to first characterize the behavior of individual wires adhered to the polymer surface under mechanical loading of the polymer.
View Article and Find Full Text PDFNat Nanotechnol
August 2025
Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.
Quantum optics has led to important advancements in our ability to prepare and detect correlations between individual photons. Its principles are increasingly translated into nanoscale characterization tools, furthering methods in spectroscopy, microscopy and metrology. In this Review, we discuss the rapid progress in this field driven by advanced technologies of single-photon detectors and quantum-light sources, including time-resolved single-photon counting cameras, superconducting nanowire single-photon detectors and entangled photon sources of increasing brightness.
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