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The products of the SuFEx reaction between sulfonimidoyl fluorides and phenols, sulfonimidates, are shown to display dynamic covalent chemistry with other phenols. This reaction was shown to be enantiospecific, finished in minutes at room temperature in high yields, and useful for both asymmetric synthesis and sustainable polymer production. Its wide scope further extends the usefulness of SuFEx and related click chemistries.
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http://dx.doi.org/10.1002/anie.202207456 | DOI Listing |
Chem Sci
September 2025
Institut für Organische Chemie, Universitat Würzburg 97074 Würzburg Germany
The reversible covalent bond formation that underpins dynamic covalent chemistry (DCC) enables the construction of stimuli-responsive systems and the efficient assembly of complex architectures. While most DCC studies have focused on systems at thermodynamic equilibrium, there is growing interest in systems that operate away from equilibrium-either by shifting to a new free-energy landscape in response to a stimulus, or by accessing an out-of-equilibrium state following an energy input. Imine-based systems are especially attractive due to the accessibility of their building blocks and their dynamic behavior in both condensation and transimination reactions.
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
School of Physics, Nanjing University of Science and Technology, Nanjing 210094, China.
Multifunctional materials that simultaneously possess intrinsic magnetic and superhard properties, particularly those composed of light elements, have a wide range of applications in advanced sensors, shielding, durable devices, and other fields. However, research on the development and understanding of such materials remains limited. In this study, a series of 3D C covalent networks derived from the C fullerene precursor were theoretically designed.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
State Key Laboratory of Petroleum Molecular & Process Engineering, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.
The discovery of new weak supramolecular interactions and supramolecular synthons is essential for directing self-assembly processes with enhanced precision, diversity, and functionality in complex molecular architectures. Here, we report the controlled self-assembly of diverse supramolecular architectures by a new directional bonding approach through the integration of radical-based dynamic covalent chemistry and supramolecular synthons. A novel macrocyclic synthon, , with a linear direction is constructed via radical-based dynamic covalent bonds from the phenothiazine building block substituted with two dicyanomethyl radicals.
View Article and Find Full Text PDFACS Macro Lett
September 2025
Pritzker School of Molecular Engineering, The University of Chicago, Chicago, Illinois 60637, United States.
Introducing dynamic covalent chemistries into polymer networks allows access to complex linear viscoelasticity, owing to the reversible nature of the dynamic bonds. While this macroscopic mechanical behavior is influenced by the dynamic exchange of these chemistries, connecting the microscopic dynamics to the bulk properties is hindered by the time scale conventional techniques can observe. Here, light scattering passive microrheology is applied to probe short-time dynamics of dynamic covalent networks that consist of telechelic benzalcyanoacetate (BCA) Michael acceptors and thiol-functionalized cross-linkers.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
College of Smart Materials and Future Energy, Fudan University, Songhu Road 2005, Shanghai, 200438, P.R. China.
Solar-driven photocatalytic oxygen reduction reaction using covalent organic frameworks (COFs) offers a promising approach for sustainable hydrogen peroxide (HO) production. Despite their advantages, the reported COFs-based photocatalysts suffer insufficient photocatalytic HO efficiency due to the mismatched electron-proton dynamics. Herein, we report three one-dimensional (1D) COF photocatalysts for efficient HO production via the hydrogen radical (H•) mediated concerted electron-proton transfer (CEPT) process.
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