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Three-species cyclic predator-prey systems are known to establish spiral waves that allow species to coexist. In this study, we analyze a structured heterogeneous system which gives one species an advantage to escape predation in an area that we refer to as a habitat and study the effect on species coexistence and emerging spatiotemporal patterns. Counterintuitively, the predator of the advantaged species emerges as dominant species with the highest average density inside the habitat. The species given the advantage in the form of an escape rate has the lowest average density until some threshold value for the escape rate is exceeded, after which the density of the species with the advantage overtakes that of its prey. Numerical analysis of the spatial density of each species as well as of the spatial two-point correlation function for both inside and outside the habitats allow a detailed quantitative discussion. Our analysis is extended to a six-species game that exhibits spontaneous spiral waves, which displays similar but more complicated results.
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http://dx.doi.org/10.1103/PhysRevE.105.054401 | DOI Listing |
Appl Biochem Biotechnol
September 2025
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, 51452, Qassim, Saudi Arabia.
Viruses are minuscule entities that cannot survive independently without a Living host. Pathogenic viruses pose a significant threat to global health, resulting annually in the deaths of thousands of people. Recent studies indicate that medicinal plants may serve as an effective source of sustainable natural antiviral agents.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2025
Navy Special Medical Centre, Second Military Medical University, Shanghai, China.
Radiation exposure initiates a cascade of reactions, including the release of reactive oxygen species, DNA double-strand breaks, and cellular apoptosis, leading to cell death, tissue damage, and potentially the development of cancer. Consequently, there is an urgent need to develop highly effective and low-toxicity radioprotective agents. Traditional chemically synthesized protective agents face significant limitations in clinical applicability due to their pronounced off-target toxicity, narrow therapeutic window, and high production costs.
View Article and Find Full Text PDFNat Protoc
September 2025
Department of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Structural biology is fundamental to understanding the molecular basis of biological processes. While machine learning-based protein structure prediction has advanced considerably, experimentally determined structures remain indispensable for guiding structure-function analyses and for improving predictive modeling. However, experimental studies of protein complexes continue to pose challenges, particularly due to the necessity of high protein concentrations and purity for downstream analyses such as cryogenic electron microscopy.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
School of Materials, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. Electronic address:
Harnessing the significant buildup of lactic acid (LA) within the tumor microenvironment (TME) for metabolic manipulation presents a promising avenue for cancer treatment. Nevertheless, single-agent therapies often fail to address the complex and varying needs of TME heterogeneity, posing a substantial scientific hurdle in oncology. In this context, we employ asymmetric mesoporous silica nanoparticles (AMS NPs) as delivery vehicles, simultaneously loading them with zinc‑cobalt‑manganese ferrite nanoparticles (ZCMF NPs), lactate oxidase (LOX), and doxorubicin (DOX).
View Article and Find Full Text PDFAnnu Rev Entomol
September 2025
2Department of Animal Physiology, Zoological Institute and Museum, University of Greifswald, Greifswald, Germany.
The evolutionary success of insects may be partly attributed to their profound ability to adjust metabolism in response to environmental stress or resource variability at a range of timescales. Metabolic flexibility encompasses the ability of an organism to adapt or respond to conditional changes in metabolic demand and tune fuel oxidation to match fuel availability. Here, we evaluate the mechanisms of metabolic flexibility in insects that are considered short-term, medium-term, and long-term responses.
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